Pathogenesis and Acute Clinical-pathological Feature of Carotid Artery Stenosis and Occlusion

颈动脉狭窄闭塞的发病机制及急性临床病理特征

• 批准号: 13671424
• 负责人: ENDO Shunro
• 金额: $ 2.05万
• 依托单位: TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13671424/
• 关键词: atheroma-thrombus; carotid artery stenosis; carotid artery occlusion; plateletaggregation; heparincofactor II; clamidia pneumonia; heparin; アテローム硬化; 頚動脈閉塞; 頚動脈狭窄; chlamydia pneumoniae; 頚動脈高度狭窄; 病理形態; ヘパリン コファクターII

The purpose of this study is to approach pathogenesis and acute clinical-pathological feature of the carotid artery stenosis and occlusion. During 2 year research periods, the following three subjects were revealed as new evidence in this field, and important topics were reported in the journal1 Clinico-pathological findings of chlamidia pneumonia of the carotid artery stenosis2 Physiological and pathological mechanisms of heparin cofactor II3 Monitoring of platelet aggregation and heparin activation in patients undergoing neuroendovascular treatment or angiographyBased on these studies, we continued research to investigate true pathological features of the carotid artery disease and to create the most adequate treatment selection and methods

这项研究的目的是处理颈动脉狭窄和闭塞的发病机理和急性临床病理学特征。在两年的研究期内，在该领域中揭示了以下三名受试者，并在《颈动脉狭窄狭窄的肺炎肺炎肺炎的临床病理学发现》杂志上报道了重要主题。2研究颈动脉疾病的真实病理特征的研究，并创建最适当的治疗选择和方法

项目成果

Hayakawa Y, Endo S, et al.: "Mechanism of activation of heparin cofactor II by calcium spitulan"Arch Biochem Biophys. 416. 47-52 (2003)

Hayakawa Y、Endo S 等人：“spitulan 钙激活肝素辅因子 II 的机制”Arch Biochem Biophys。

Hayashi N, Endo 5, et al.: "Surgical outcome of the carotid artery stenosis"Cerebrovascular Surgery (in Japanese). 30. 387-391 (2002)

Hayashi N、Endo 5 等：“颈动脉狭窄的手术结果”脑血管外科（日语）。

Hirashima Y, Endo S, et al.: "Chlamidia pneumonia infection is not involved in carotid artery Stenosis."Atherosclerosis. 163. 165-168 (2002)

Hirashima Y、Endo S 等人：“肺炎衣原体感染不涉及颈动脉狭窄。”动脉粥样硬化。

Hayakawa Y, Endo S, et al.: "Mechanism of activation of heparin cofactor II by calcium spitulan"Arch Biochem Biophys. 415. 47-52 (2003)

Hayakawa Y、Endo S 等人：“spitulan 钙激活肝素辅因子 II 的机制”Arch Biochem Biophys。

遠藤俊郎, 平島 豊, 他: "急性期脳虚血患者に対する緊急CEAの適応と手術の要点"脳神経外科ジャーナル. 11. 396-401 (2002)

Toshiro Endo、Yutaka Hirashima 等：“急性脑缺血患者的紧急 CEA 适应症和手术要点”《神经外科杂志》11. 396-401 (2002)。