Fund a mental research for treatment of keloid and hypertrophic scar
Fund a mental research for treatment of keloid and hypertrophic scar
批准号:
16591805
负责人:
UEDA Koichi
金额:
$0.96万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2004
资助国家:
日本
项目状态:
已结题
起止时间:
2004 至 2006
中文摘要
我们以前已经表明,瘢痕疙瘩的三磷酸腺苷(ATP)含量长期保持较高水平。在瘢痕疙瘩中,无氧糖酵解可能与ATP的产生有关。在这项研究中,我们计数血管瘢痕疙瘩,增生性和萎缩性瘢痕在一个定义的区域,并测量其内腔的横截面积免疫组织病理学和乳酸浓度。瘢痕疙瘩中定义区域的平均数量最小,血管的平均内部面积也最小。减少和狭窄的血管可能减少氧灌注。瘢痕疙瘩的血液供应不足,这仍然存在。
英文摘要
We have previously shown that the adenosine triphosphate (ATP) content of keloids remains high for a long time. In keloids, anaerobic glycolysis may be related to the production of ATP. In this study, we counted the vessels in keloids, hypertrophic and atrophic scars in a defined area, and measured the cross-sectional areas of their internal lumens immunohistopathologically and the lactate concentrations. The mean number in a defined area was smallest in keloids as was the mean internal area of vessels. The decreased and narrowed vessels may reduce oxygen perfusion. The blood supply to keloids is inadequate, and this persists.
期刊论文(8)
专著(0)
科研奖励(0)
会议论文
DOI:
10.1080/02844310410029552
发表时间:
2004-11-01
期刊:
SCANDINAVIAN JOURNAL OF PLASTIC AND RECONSTRUCTIVE SURGERY AND HAND SURGERY
影响因子:
--
作者:
[Ueda, K, Yasuda, Y, Oba, S]
通讯作者:
Oba, S
海外基金