Development of a moisturized soft denture liner for a patient having dry mouth

许多老年病人主诉口干和不适。据报道，65岁以上的人中有56.1%的人意识到口干。因此，有必要尽快解决这个问题。对于口腔干燥的患者，即使使用硬基托树脂和软基托衬，由于固位和稳定性不足，以及/或咀嚼疼痛，大多数义齿的制作效果都不满意。本研究的目的是开发一种适合于口腔干燥和严重吸收残牙的患者的湿润软性义齿衬垫。2004年测定了商品义齿粘接剂和唾液替代凝胶的动态粘弹性和与义齿基托树脂的结合强度。在临时软衬材料的情况下，聚合物粉末分子量、增塑剂类型、乙醇含量和粉液比对凝胶特性的影响（Journal of Dental Research, 2005）。2005年，对上述成分和结构对临时软衬材料动态粘弹性能的影响进行了评价。对自聚合丙烯酸软性义齿衬垫进行了粘弹性性能与单体类型关系的附加实验。论文正在准备中。另一方面，研究了软性义齿衬垫的咀嚼功能与粘弹性的关系。研究发现，具有粘弹性特性的软性义齿衬套应用于全口义齿比具有弹性特性的软性义齿衬套对咀嚼功能的改善更为显著。在上述结果的基础上，确定了适合口腔干燥患者的湿润软性义齿衬垫的成分和结构。目前对该材料的力学性能和功能效果进行了评价。

Many elderly patients complaint of dry mouth and discomfort. It has been reported that 56.1% of the people above 65 years old aware of dry mouth. Thus, it is necessary to dissolve this problem as soon as possible. Clinically satisfied results are not obtained in the most of fabrication of dentures for the patients having dry mouth even if hard denture base resin and soft denture liner are applied, because of insufficient retention and stability, and/or masticatory pain. The purpose of this study was to develop a moisturized soft denture liner suitable for thee patients having dry mouth and severe absorbed residual ridge.In 2004, the dynamic viscoelastic properties and bond strength to denture base resins of commercial denture adhesives and saliva replacement gels were determined. In the case of temporary soft lining materials, influence of molecular weight of polymer powders, plasticizer type, ethyl alcohol content and powder/liquid ratio on gelation characteristics (Journal of Dental Research, 2005).In 2005, influence of above mentioned composition and structure on dynamic viscoelastic properties of temporary soft lining materials was evaluated. For the autopolymerized acrylic soft denture liners, the additional experiment concerning relationship between viscoelastic properties and type of monomer was conducted. The paper is being prepared now. On the other hand, relationship between masticatory function and viscoelastic properties of soft denture liners has been determined. It has been found that the application of a soft denture liner having viscoelastic properties to the complete denture leads to more marked improvement in masticatory function than that of a soft denture liner having elastic properties. On the basis of the above results, the composition and structure suitable for the moisturized soft denture liner for a patient having dry mouth were determined. At present, mechanical properties and functional effects of this material is evaluated.