Development of tissue conditioner with moisture effect for dry mouth

开发具有保湿效果的口干组织调理剂

• 批准号: 18592126
• 负责人: MURATA Hiroshi
• 金额: $ 2.41万
• 依托单位: Nagasaki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2006
• 资助国家: 日本
• 起止时间: 2006 至 2007
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18592126/
• 关键词: Tissue conditioner; Dry mouth; Viscoelasticity; Denture adhesive; Ethyl alcohol; Oral moisture gel

The purpose of this research is to develop tissue conditioner with moisture effect kir dry mouth.In 2006, we conducted the research concerning a non-alcohol tissue conditioner to improve the durability. This study was evaluated by means of setting characteristics using the displacement rheometer and dynamic viscoelastic properties using the non-resonance forced vibration method. This tissue conditioner is applied for longer period than the previous one because this material does not contain the ethyl alcohol in the liquids. A part of the results has been published in Journal of Dentistry. We also established the evaluation method of viscosity of oral moisture gel and denture adhesives having lower viscosity. This measurement has been conducted by means of a Sine-wave Vibro Viscometer.In 2007, the water absorption, solubility and compatibility with dental stones of tissue conditioners were evaluated. A part of the results is planned to be publishes in Dental Materials Journal. The relationship between composition and mechanical properties of the heat-polymerized and auto-polymerized acrylic denture liners has been evaluated. These results have been presented in the congress and now the paper is being prepared. The viscosity is very important for the evaluation of these materials in addition to the physical properties after setting. The viscosity of commercial oral moisture gel and cream type denture adhesives was determined. We plan to conduct clinical test using trial tissue conditioner. The evaluation method of masticatory function was established and this has been presented in Journal of Oral Rehabilitation. The suitable composition of trial tissue conditioner has been determined from the experimental results. We are conducting the experiment concerning the effect of moisture materials and evaluating the mechanical properties.

本研究的目的是开发具有滋润效果、缓解口干的组织调理剂。2006年，我们进行了无酒精组织调理剂的研究，以提高其持久性。本研究通过使用位移流变仪的设定特性和使用非共振强迫振动法的动态粘弹性特性进行评估。这种组织调理剂的使用时间比前一种组织调理剂的使用时间更长，因为这种材料在液体中不含乙醇。部分结果发表在《牙科杂志》上。我们还建立了口腔保湿凝胶和粘度较低的义齿粘合剂的粘度评价方法。该测量是通过正弦波振动粘度计进行的。2007年，对组织调理剂的吸水性、溶解性以及与牙石的相容性进行了评估。部分结果计划发表在《牙科材料杂志》上。对热聚合和自聚合丙烯酸义齿衬垫的成分和机械性能之间的关系进行了评估。这些结果已在大会上提出，目前论文正在准备中。除了凝固后的物理性能外，粘度对于评价这些材料也非常重要。测定了市售口腔保湿凝胶和乳膏型义齿粘合剂的粘度。我们计划使用试验组织调理剂进行临床测试。建立了咀嚼功能评价方法，并发表在Journal of Oral Rehabilitation杂志上。根据实验结果确定了试验组织调理剂的合适组成。我们正在进行有关水分材料影响的实验并评估其机械性能。

项目成果

PVM-MAの含有量が義歯安定剤の粘度および粘着力に及ぼす影響

PVM-MA含量对义齿粘合剂粘度和粘合强度的影响

• 发表时间: 2007
• 作者: Hong;G;奥山 義和;林田 健太郎
• 通讯作者: 林田 健太郎

酵素が軟質義歯裏装材の理工学的性質に及ぼす影響

酶对软义齿衬里材料科学和工程性能的影响

• 发表时间: 2006
• 作者: Hukuda;T;Hong G;李 英愛
• 通讯作者: 李 英愛

16.義歯の再装着と咬合調整、設計例28、パーシャルデンチャーテクニック[第4版](野首孝祠、井上宏、細井紀雄、五十嵐順正編)

16. 假牙修复和咬合调整，设计实例28，局部假牙技术[第4版]（由Takashi Nokubi、Hiroshi Inoue、Norio Hosoi、Junmasa Igarashi编辑）

• 发表时间: 2006
• 作者: Hong;G;村田 比呂司(分担)
• 通讯作者: 村田 比呂司(分担)

16. 義歯の再装着と咬合調整、設計例28、パーシャルデンチャーテクニック [第4版] (野首孝祠, 井上 宏, 細井紀雄, 五十嵐順正 編)

16. 假牙修复和咬合调整，设计实例28，局部假牙技术[第4版]（由Takashi Nokubi、Hiroshi Inoue、Norio Hosoi、Junmasa Igarashi编辑）

• 发表时间: 2006
• 作者: Hong;G;村田 比呂司(分担);村田比呂司(分担)
• 通讯作者: 村田比呂司(分担)

Automatic regulation of occlusal force because of hardness change of the bite obiect

根据咬合物体的硬度变化自动调节咬合力

• 发表时间: 2008
• 期刊: Journal of Oral Rehabilitation 35
• 作者: Hirata;I;Shimada A
• 通讯作者: Shimada A