Research on Molecular Target therapy for Acral Melanoma
Research on Molecular Target therapy for Acral Melanoma
批准号:
20591318
负责人:
MURATA Hiroshi
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
To personalize the therapy with molecular targeting therapy for melanoma, we showed that : 1. two of 28 case had activating mutation of KIT gene and one of these mutation, D820Y, was sensitive to the sunitinib. 2. Circulating melanoma cells could extract by using anti-HMW-MAA antibody and we detect the BRAF mutation states from them. 3. We showed polyclonality of melanoma cells on BRAF mutation states.
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DOI:
10.1111/j.1755-148x.2009.00645.x
发表时间:
2010-02
期刊:
Pigment Cell & Melanoma Research
影响因子:
4.3
作者:
[M. Takata;H. Murata;T. Saida]
通讯作者:
M. Takata;H. Murata;T. Saida
Pathological activation of KIT is common in acral and mucosal melanomas.
KIT 的病理激活常见于肢端和粘膜黑色素瘤。
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Ashida A, Takata M, Murata H, Kido K, Saida T.]
通讯作者:
Saida T.
Pathological activation of KIT in acral and mucosal melanomas.
KIT 在肢端和粘膜黑色素瘤中的病理激活。
DOI:
--
发表时间:
2009
期刊:
Int J Cancer 124
影响因子:
--
作者:
[Ashida A, Takata M, Murata H, Kido K, Saida T]
通讯作者:
Saida T
NADPH oxidase (Nox) 4 contribute to transformation phenotype of melanoma cells by regulating G2-M cell cycle progression.
NADPH 氧化酶 (Nox) 4 通过调节 G2-M 细胞周期进程促进黑色素瘤细胞的转化表型。
DOI:
--
发表时间:
2009
期刊:
Cancer Res 69
影响因子:
--
作者:
[Yamaura M, Mitsushita J, Furuta S, Kiniwa Y, Ashida A, Goto Y, Shang WH, Kubodera M, Kato M, Takata M, Saida T, Kamata T]
通讯作者:
Kamata T
DOI:
10.1038/sj.bjc.6606072
发表时间:
2011-02-01
期刊:
British journal of cancer
影响因子:
8.8
作者:
[]
通讯作者:
共 14 条
Development of dynamic-impression type light-cured soft denture liners with photocatalyst function and healing acceleration function
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批准号:17H04393
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.98万
-
财政年份:2017
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负责人:MURATA Hiroshi
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依托单位:
Development of mouth moisturizer with functions of acceleration of salivary secretion and activation of mucosa for denture patients with dry mouth
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批准号:16K15806
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.16万
-
财政年份:2016
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负责人:MURATA Hiroshi
-
依托单位:
Development of a multi-function soft denture liner having bFGF-controlled release and self-cleaning functions
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批准号:26293413
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.57万
-
财政年份:2014
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负责人:MURATA Hiroshi
-
依托单位:
Investigation of visual field employing Bayes and machine learning method
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批准号:25861618
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.41万
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财政年份:2013
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负责人:MURATA Hiroshi
-
依托单位:
Pre-equalizing high-speed electro-optic modulator utilizing polarization reversal technology
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批准号:24360135
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.06万
-
财政年份:2012
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负责人:MURATA Hiroshi
-
依托单位:
Development of millimeter-wave/THz-wave generation devices utilizing a high-Q resonator and nonlinear-optical difference frequency generation
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批准号:24656233
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.58万
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财政年份:2012
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负责人:MURATA Hiroshi
-
依托单位:
Development of a mouth moisturizer using the colloidal platinum and chymase inhibitor.
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批准号:24659863
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项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2012
-
负责人:MURATA Hiroshi
-
依托单位:
Development of a fluorinated tissue conditioner with high durability and healing acceleration function by bioactive substances
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批准号:23390446
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.56万
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财政年份:2011
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负责人:MURATA Hiroshi
-
依托单位:
Research on advanced wireless-optical signal converters utilizing optical modulation technique in polarization-reversal structures
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批准号:21360170
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.23万
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财政年份:2009
-
负责人:MURATA Hiroshi
-
依托单位:
Development of an antimicrobial soft denture liner having the moisture effect and photocatalytic function for patients with dry mouth
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批准号:20390491
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.65万
-
财政年份:2008
-
负责人:MURATA Hiroshi
-
依托单位:
Development of tissue conditioner with moisture effect for dry mouth
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批准号:18592126
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.41万
-
财政年份:2006
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负责人:MURATA Hiroshi
-
依托单位:
Study on ultra-fast optical polarization modulators/polarization-manipulation devices using electro-optic effects
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批准号:18360172
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.74万
-
财政年份:2006
-
负责人:MURATA Hiroshi
-
依托单位:
Study on high-speed optical frequency shifter utilizing polarization-reversal structure
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批准号:16360174
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.66万
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财政年份:2004
-
负责人:MURATA Hiroshi
-
依托单位:
Development of a moisturized soft denture liner for a patient having dry mouth
-
批准号:16591953
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.18万
-
财政年份:2004
-
负责人:MURATA Hiroshi
-
依托单位:
Development of functional soft denture liners without environmental endocrine disruptors
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批准号:13672036
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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财政年份:2001
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负责人:MURATA Hiroshi
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依托单位:
Development of antimicrobial tissue conditioners without ethvl alcohol based on sebacate ester
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批准号:11671936
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.56万
-
财政年份:1999
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负责人:MURATA Hiroshi
-
依托单位:
海外基金