Development of bonding system for altered dentin

改变牙本质粘合系统的开发

• 批准号: 16591970
• 负责人: AIDA Masahiro
• 金额: $ 2.3万
• 依托单位: Nihon University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2004
• 资助国家: 日本
• 起止时间: 2004 至 2005
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-16591970/
• 关键词: N-methacryloyl-ω-alkylamino; self-etching primer; interaction; decalcification

It is well understood that the bond strength of resin to the dentin decreased when the storage period of self-etching primers is prolonged, due to the alteration of the functional monomers employed in the primer.In this study, we prepared a series of five altered self-etching primers with different degradated stages. The degradation stage effects of self-etching primer on the bond strength of resin to the dentin were examined to understand the degradation mechanism on the dentin bonding through the alteration of the functional monomer employed in self-etching primer.When the fresh liquid A, where the HEMA had hydrolyzed by 5%, was applied to the ED Primer II bonding system, the mean bond strength of resin to dentin was approximately 12 MPa. This initial mean bond strength to the dentin, conditioned by the altered ED Primer II, was maintained until the HEMA utilized in the liquid A had hydrolyzed by 62%.Furthermore, when the amount of hydrolyzed HEMA become more than 62%, the bond strength dramatically dropped down to 8 MPa. This dramatic decrease was probably due to the degradation of the priming efficacy of the dentinal collagen network by the HEMA.The degradation of the liquid A, caused by the hydrolysis of the methacryloxy ester portion in the HEMA, induces a decrease in the bond strength. Specifically, when HEMA in the liquid A had hydrolyzed by 67%, the dramatic decrease in the bond strength to the dentin was observed. We found the initial bond strength was maintained until the amount of hydrolyzed HEMA reached to 62%.

众所周知，随着自酸蚀底漆储存时间的延长，由于底漆中使用的功能单体的改变，树脂与牙本质的粘结强度会下降。通过改变自酸蚀底漆中使用的功能单体，考察自酸蚀底漆对牙本质树脂粘结强度的降解阶段效应，以了解自酸蚀底漆对牙本质粘结的降解机理。将HEMA水解液5%的新鲜A液应用于ED Primer II粘接系统，树脂与牙本质的粘结强度平均约为12 Mpa。在改变的ED Primer II的条件下，初始的牙本质平均粘结强度一直保持到液体A中使用的HEMA水解量达到62%为止。此外，当水解量超过62%时，粘结强度急剧下降到8 Mpa。这种显著的下降可能是由于HEMA降低了牙本质胶原网络的启动效率。液体A的降解是由于HEMA中的甲基丙烯氧基酯部分的水解导致的，导致粘结强度的下降。具体地说，当液体A中的HEMA水解67%时，观察到与牙本质的粘结强度显著下降。我们发现，在HEMA水解量达到62%时，初始粘结强度一直保持不变。

项目成果

Development of adhesive primer for resin core construction

树脂芯结构用粘合底漆的开发

• 发表时间: 2006
• 期刊: Dental Materials Journal 25・3(掲載予定)
• 作者: Takeo SUGA;et al.;高橋英和;小林雅博;岩崎直彦;會田雅啓;Takahashi H;Misako Odaki
• 通讯作者: Misako Odaki

Effectiveness of methacrylamid monomer for dentin bonding

甲基丙烯酰胺单体对牙本质粘合的有效性

• 发表时间: 2006
• 期刊: The Journal of Japan Prosthodontic Society, 50/3 (Publication Schedule)
• 作者: Takeo SUGA;et al.;高橋英和;小林雅博;岩崎直彦;會田雅啓;Takahashi H;Misako Odaki;Kobayashi M;Aida Masahiro
• 通讯作者: Aida Masahiro

Development of adhesive prime for resin core construction

开发树脂芯结构用粘合剂底漆

• 发表时间: 2006
• 期刊: Dental Materials Journal, 25/3 (Publication Schedule)
• 作者: Takeo SUGA;et al.;高橋英和;小林雅博;岩崎直彦;會田雅啓;Takahashi H;Misako Odaki;Kobayashi M;Aida Masahiro;Misako Odaki
• 通讯作者: Misako Odaki

象牙質接着性モノマーとしてのメタクリルアミドモノマーの有用性について

甲基丙烯酰胺单体作为牙本质粘合剂单体的用途

• 发表时间: 2006
• 期刊: 日本補綴歯科学会雑誌 50・3(掲載予定)
• 作者: Takeo SUGA;et al.;高橋英和;小林雅博;岩崎直彦;會田雅啓
• 通讯作者: 會田雅啓