权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

A Study on the intravenous sedation with propofol - Function of Swallowing, BIS monitor and blood concentration of propofol -

异丙酚静脉镇静研究-吞咽功能、BIS监测及异丙酚血药浓度-

基本信息

批准号：
16591997
负责人：
SHIMADA Masahiko
金额：
$ 2.37万
依托单位：
OKAYAMA UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2004
资助国家：
日本
起止时间：
2004 至 2005
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-16591997/
关键词：
Intravenous sedation Function of Swallowing tongue pressure pharyngeal pressure Dental treatment BIS Blood concentration Pronofol 舌骨上筋群

项目摘要

Purpose : The tongue contacts to the hard palate during the pharyngeal stage of swallowing. This is essential for swallowing safety. Purpose of this study is to make up a system to measure the pressure of tongue and pharynx at a time.Methods : Ten healthy volunteers (four male and six female) with mean age of 25.5 years old (range 20-34 years old) were examined. The infusion type pressure measuring and analyzing system PowerLab (ADInstrument inc.) was used. The micro silicon tubes (IMG inc.) were installed into the experimental palatal plate for the tongue pressure sensors at the four points to measure the pressure of the four section of the tongue ; anterior (Ch.1), middle (Ch.2), posterior (Ch.3) and right or left lateral (Ch.4) sections of tongue. The manometer had some sensors to measure the pressure at the upper esophageal and the 5mm upper point from it. With this system, we measured the tongue and pharyngeal pressure during swallowing saliva.Results : The mean of the maximal pressure and the occurring timing of the pressure of each measuring points were analyzed. The subjects were identified 4 patterns by the rank order of the maximal value. Tongue pressure almost always appeared simultaneously with pharyngeal pressures appearance.Conclusion : The intra-individual variation of the pressure was small, and we identified 4 types of swallowing pressure. The occurring timing of the pressure was suggested that contact of the tongue against the hard palate affect to pharyngeal stage.

目的：在吞咽的咽阶段，舌头接触硬腭。这对于吞咽安全至关重要。本研究的目的是建立一个同时测量舌头和咽部压力的系统。方法：对10名平均年龄为25.5岁（范围20-34岁）的健康志愿者（4名男性和6名女性）进行检查。使用输液式压力测量分析系统PowerLab(ADInstrument inc.)。将微型硅管（IMG inc.）安装在实验腭板中，作为舌压传感器的四点，测量舌头四段的压力；舌头的前部 (Ch.1)、中部 (Ch.2)、后部 (Ch.3) 和右侧或左侧 (Ch.4) 部分。压力计有一些传感器来测量食管上部和距食管 5 毫米上部点的压力。通过该系统，我们测量了吞咽唾液时舌头和咽部的压力。结果：分析了每个测量点的最大压力的平均值和压力发生的时间。受试者按照最大值的排列顺序识别出 4 种模式。舌压几乎总是与咽部压力同时出现。结论：压力的个体差异较小，我们识别出4种吞咽压力。压力发生的时机提示舌头与硬腭的接触影响咽阶段。