A Study on the intravenous sedation with propofol - Function of Swallowing, BIS monitor and blood concentration of propofol -

异丙酚静脉镇静研究-吞咽功能、BIS监测及异丙酚血药浓度-

基本信息

批准号：
16591997
负责人：
SHIMADA Masahiko
金额：
$ 2.37万
依托单位：
OKAYAMA UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2004
资助国家：
日本
起止时间：
2004 至 2005
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-16591997/
关键词：
Intravenous sedation Function of Swallowing tongue pressure pharyngeal pressure Dental treatment BIS Blood concentration Pronofol 舌骨上筋群

项目摘要

Purpose : The tongue contacts to the hard palate during the pharyngeal stage of swallowing. This is essential for swallowing safety. Purpose of this study is to make up a system to measure the pressure of tongue and pharynx at a time.Methods : Ten healthy volunteers (four male and six female) with mean age of 25.5 years old (range 20-34 years old) were examined. The infusion type pressure measuring and analyzing system PowerLab (ADInstrument inc.) was used. The micro silicon tubes (IMG inc.) were installed into the experimental palatal plate for the tongue pressure sensors at the four points to measure the pressure of the four section of the tongue ; anterior (Ch.1), middle (Ch.2), posterior (Ch.3) and right or left lateral (Ch.4) sections of tongue. The manometer had some sensors to measure the pressure at the upper esophageal and the 5mm upper point from it. With this system, we measured the tongue and pharyngeal pressure during swallowing saliva.Results : The mean of the maximal pressure and the occurring timing of the pressure of each measuring points were analyzed. The subjects were identified 4 patterns by the rank order of the maximal value. Tongue pressure almost always appeared simultaneously with pharyngeal pressures appearance.Conclusion : The intra-individual variation of the pressure was small, and we identified 4 types of swallowing pressure. The occurring timing of the pressure was suggested that contact of the tongue against the hard palate affect to pharyngeal stage.

目的：在吞咽的咽阶段，舌头接触了硬pa。这对于吞咽安全至关重要。这项研究的目的是构成一个系统，以一次测量舌头和咽部的压力。方法：对十名健康志愿者（四名男性和六名女性），平均年龄为25.5岁（范围20-34岁）。使用了输注型压力测量和分析系统PowerLab（Adinstrument Inc。）。将微硅管（IMG Inc。）安装到实验性pa板上，以在四个点处，以测量舌头四个部分的压力；前（Ch.1），中间（Ch.2），后部（CH.3）和右侧或左侧（CH.4）舌头截面。该计量机具有一些传感器，可以测量上部食道和5mm上点的压力。使用该系统，我们测量了吞咽唾液期间的舌头和咽压力。分析：最大压力的平均值和每个测量点的压力的发生时机。通过最大值的等级顺序识别受试者的4个模式。舌头压力几乎总是以咽压的外观同时出现。结论：压力的个体内部变化很小，我们确定了4种吞咽压力。表明，压力的发生时机表明，舌头与硬pa的接触与咽阶段的接触。