Effects of pre-warming and aging on the core and peripheral temperatures

预热和老化对核心和外围温度的影响

• 批准号: 17591622
• 负责人: MATSUKAWA Takashi
• 金额: $ 2.18万
• 依托单位: University of Yamanashi
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2005
• 资助国家: 日本
• 起止时间: 2005 至 2006
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-17591622/
• 关键词: temperature; aging; core; peripheral; pre-warming; premedication; thermoregulation

The volunteers' height was 169 ± 7 (162-177) cm, total body mass (TBM) 65 ± 12 (55-85) kg, and age 33 ± 4 (27-36) yr. The lean body mass (LBM) was 52 ± 7 (45-64) kg as determined from height (cm) and TBM (kg) using a formula ; LBM = (1.10TBM)-128(TBM/height)^2. Basal surface area was 1.8±0.2 (1.6-2.1) m2. Sedation scores 30 minutes after administration of midazolam in volunteers with midazolam premedication (0.075 mg kg^<-1>, with or without forced-air warming) were significantly lower than those without intramuscular midazolam administration.Tympanic membrane temperature (T_<tym>) of the group with forced-air warming + midazolam decreased until 20 min after i.m. midazolam, however afterwards it increased significantly compared with T_<tym> of the group with midazolam i.m. without warming. Forearm minus finger tip and calf minus toe, skin-temperature gradients did not differ significantly among the three groups. Mean skin temperatures of 30 min after midazolam intramuscular administration in the group with i.m. midazolam was significantly lower than those in the other two groups.In conclusion, we can conclude that forced-air warming after premedication with midazolam is important to prevent anaesthesia-induced redistribution hypothermia.

受试者身高169 ± 7（162-177）cm，总体重（TBM）65 ± 12（55-85）kg，年龄33 ± 4（27-36）岁。瘦体重（LBM）为52 ± 7（45-64）kg，根据身高（cm）和体重（kg）计算公式：LBM =（1.10 TBM）-128（TBM/身高）^[2]。基底表面积为1.8±0.2（1.6-2.1）m2。肌注咪达唑仑（0.075mg/kg）后30 min镇静评分<-1>显著低于未肌注咪达唑仑组（P &lt; 0.01），而肌注咪达唑仑<tym>+咪达唑仑组鼓膜温度（T_（10））下降至肌注后20 min。咪达唑仑组T_1较咪达唑仑组显著升高，但<tym>与咪达唑仑组比较，T_1较咪达唑仑组显著升高。没有温暖。前臂-指尖和小腿-足趾的皮肤温度梯度在三组之间没有显著差异。肌注咪达唑仑组肌注咪达唑仑后30 min的平均皮肤温度咪达唑仑显著低于其他两组。总之，我们可以得出结论，咪达唑仑术前用药后强制空气加温对预防麻醉诱导的再分布低温很重要。