Star and Amphiphilic Responsive Anisotropic Colloids: Design and Self-Assembly

星型和两性响应各向异性胶体：设计和自组装

• 批准号: 490663365
• 负责人: Professor Dr. Jérôme Crassous, Ph.D.
• 金额: --
• 依托单位: Lehrstuhl für Physikalische Chemie II
• 依托单位国家: 德国
• 项目类别: Research Grants
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/490663365?language=en
• 关键词: Star; Amphiphilic; Responsive; Anisotropic; Colloids

Hybrid colloids with tunable star architectures will be designed from bioengineered filamentous fd viruses acting as arms specifically associated with thermo-responsive microgels as a mesoscale analog of star block copolymers. The formation of these new colloidal polymers relies on the complementary expertise of Aachen on functional microgels and their use as model soft colloids and Bordeaux on rod-like viruses and their tip functionalization. Benefiting from the large persistence length of the rod-shaped virus, such colloidal copolymers are expected to offer a novel extremely long-range soft potential and a rich phase diagram that will be investigated both in the direct and reciprocal space combining microscopy and scattering techniques. These colloidal polymer stars with tunable spatial distribution of the viral arms will allow for dynamics study at the single particle scale. Finally, by reducing the valency to one virus linked to one microgel or by specifically functionalizing the microgels, amphiphilic hybrids will be produced with the ultimate goal to create colloidal analogs mimicking molecular systems and being observable at the single particle level of block copolymers and surfactants. According to their effective packing parameters, these amphiphilic colloids will self-organize into defined hierarchical assemblies, as spherical, worm-like or vesicular superstructures, opening the way of a better understanding of their self-assembly processes and phase transitions.

具有可调星形结构的混合胶体将由生物工程丝状 fd 病毒设计而成，该病毒作为与热响应微凝胶（作为星形嵌段共聚物的介观类似物）专门相关的臂。这些新型胶体聚合物的形成依赖于亚琛在功能性微凝胶及其作为模型软胶体方面的专业知识和波尔多在棒状病毒及其尖端功能化方面的互补专业知识。受益于杆状病毒的大持久性长度，这种胶体共聚物有望提供一种新颖的极长程软势和丰富的相图，将在直接空间和倒易空间中结合显微镜和散射技术进行研究。这些具有可调病毒臂空间分布的胶体聚合物星将允许在单粒子尺度上进行动力学研究。最后，通过降低与一种微凝胶相连的一种病毒的化合价或通过对微凝胶进行专门功能化，将产生两亲性杂化物，最终目标是创建模拟分子系统的胶体类似物，并在嵌段共聚物和表面活性剂的单颗粒水平上可观察到。根据其有效堆积参数，这些两亲性胶体将自组织成定义的分层组装体，如球形、蠕虫状或囊泡状上层结构，为更好地理解其自组装过程和相变开辟了道路。