Deciphering the plasma membrane-associated responses to mechanical stress (A08*)

破译质膜对机械应力的相关反应 (A08*)

• 批准号: 493199294
• 金额: --
• 依托单位: Zentrum für Molekularbiologie der Pflanzen (ZMBP)
• 依托单位国家: 德国
• 项目类别: Collaborative Research Centres
• 财政年份: 2022
• 资助国家: 德国
• 起止时间: 2021-12-31 至 2022-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/493199294?language=en
• 关键词: Deciphering; plasma; membrane; associated; responses

How can mechanical stress trigger molecular responses? To tackle this question, we developed a microfluidic device that allows to trap living protoplasts, to induce tightly controlled mechanical stress, coupled with high-resolution microscopy. After assessing different levels of mechanical stress endured by the protoplasts, we will analyse the molecular responses triggered by mechanical stress. These results will give a better understanding of the first steps of mechano-sensing signalling and responses.

机械应力如何引发分子反应？为了解决这个问题，我们开发了一种微流体装置，可以捕获活的原生质体，诱导严格控制的机械应力，再加上高分辨率显微镜。在评估了原生质体承受的不同水平的机械应力后，我们将分析机械应力引发的分子反应。这些结果将使我们更好地理解机械感应信号和反应的第一步。