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大脳高次視覚領における視覚・内眼筋運動連関の神経機構についての研究

大脑高级视觉区视觉与眼内肌运动连接的神经机制研究

基本信息

批准号：
02255207
负责人：
板東武彦
金额：
$ 1.28万
依托单位：
Niigata University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research on Priority Areas
财政年份：
1990
资助国家：
日本
起止时间：
1990 至无数据
项目状态：
已结题

项目摘要

本研究では焦点調節(内眼筋運動)について、その手掛り刺激から制御パラメ-タを得る過程で、ネコ大脳高次視覚領の1つ(外側上シルビウス領、LSA)が果たす役割について研究を行った。実験には記録・刺激用チェンバ-を装着したネコを用いた。ケタミンで導入、笑気麻酔下でガラミンで不動化し、眼の屈折力を赤外線オプトメ-タ、瞳孔面積を赤外線瞳孔計を用いた記録した。ニュ-ロン活動の記録・脳内微小刺激にはダングステン電極を用いた。結果は次の通りであった。(1)自発性の焦点調節に先行して活動するLSAニュ-ロン(焦点調節ニュ-ロン)の60%でその活動と屈折力増加の立上り速度との間に有意な相関が認められた。(2)動物に接近・離反する視覚対象の動きに選択性を持つ視覚ニュ-ロン群の25%は焦点調節ニュ-ロンであった。(3)本研究経費で制作した視覚刺激装置を用い、視標の接近・離反運動に含まれる視覚刺激要素を分離した結果、焦点調節ニュ-ロンは視標の大きさ変化に応答し、両眼視差の変化には応じなかった。前者は焦点調節の動的要素を引き起こす重要な手掛り刺激であり、従ってこれらのLSA焦点調節ニュ-ロン群は焦点調節系における視覚・運動連関の接点の1つであると結論した。(4)脳内微小刺激と解剖学的標識を組合せ、LSA内焦点調節領域から瞳孔領域に到る機能的結合を示した。以上の結果から、LSAは自己とその周囲空間との相対的位置関係の視覚的分析のみではなく、焦点調節にかかわる視覚情報が運動系へ受け渡される過程、すなわち視覚・内眼筋運動連関に寄与することが示された。

The purpose of this study is to focus on the training of the internal eye muscles, the stimulation of the hand, the improvement of the process, and the results of the study. In this study, the focus of this study is to focus on the internal muscle movement (internal muscle movement), manual stimulation, control and treatment. (LSA). Please note that the stimulus is to be used as a stimulus. The eye bending force, the external contact force, the pupil surface, the pupil, the pupil and the pupil were recorded. Small stimuli in the activity log do not affect the use of active electricity. Results the results showed that there were significant differences between the two groups. (1) the first step of LSA focus is to increase the bending force of 60% of the activity. (2) the animal is close to the image of the animal. It is optional to support the focus of 25% of the group. (3) the purpose of this study is to make a real-time stimulus device, which is close to the anti-action device, including the results of the separation of the stimulus elements, the focus, the response, and the difference of the eye. The elements of the former focus activities lead to the important handsets that stimulate the LSA focus, the focus of the crowd, the focus of the contact, the contact of the contact, and the results of the discussion. (4) the combination of anatomy of microstimuli and the combination of focal domain and pupil domain in LSA. The results of the above results, the analysis of the location where the space is in contact with each other, the analysis of the LSA, the analysis of the location of the weekly space contact, the analysis of the location of the weekly space contact, the analysis of the location of the weekly space contact, the analysis of the location of the weekly space contact, the analysis of the location of the weekly space contact, the analysis of the location of the weekly space contact, the analysis of the location of the weekly space contact, the analysis of the location of the weekly space contact, the analysis of the location of the weekly space contact, the analysis of the location of the weekly space contact, the analysis of the location of the weekly space contact, the analysis of the location of the weekly space contact, the analysis of the location of the weekly space contact, the analysis of the location of the weekly space contact, the analysis of the location of the weekly space contact, the analysis of the location of the