近見反応の大脳内階層的情報処理機構についての研究(2)

近视反应的大脑分层信息处理机制研究（二）

• 批准号: 06260215
• 负责人: 板東 武彦
• 金额: $ 1.28万
• 依托单位: Niigata University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research on Priority Areas
• 财政年份: 1994
• 资助国家: 日本
• 起止时间: 1994 至 无数据
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-06260215/
• 关键词: 視覚運動連関; 近見反応; 輻輳運動; 眼球運動; 大脳; 神経生理学

本研究では近見反応の内,輻輳運動について大脳LS皮質(PMLS野)内の異なる微小分野が果たす役割について分析した。実験には,接近する視標に対して輻輳運動を行なうよう訓練したネコを用いた。1.LS皮質(PMLS野)の尾側中心視領域を片側局所破壊すると,輻輳運動の振幅・ピーク速度が減少し,輻輳運動の左・右眼成分が非対称となった。破壊後1ヶ月では,輻輳運動の振幅・ピーク速度の減少は回復しなかったが,輻輳運動の左右眼の対称性は回復した。この結果,正常の対称性輻輳運動にPMLS野尾側部が必要なこと,この機能は他の分野により代償されうることが示された。前者は脳内刺激によりPMLS野吻側部から左右非対称,尾側部から左右対称の輻輳運動が誘発されることと一致した。2.1)視標接近中にPMLS野の尾側輻輳運動領域に対し脳内微小刺激を繰り返し与えた(55試行,20分間)。その後,数時間-1日にわたり,視覚刺激単独で誘発される輻輳運動の振幅・ピーク速度が有意に増加した。(2)輻輳運動増強を確認後,PMLS皮質の当該領域にグルタミン酢非NMDA型受容体遮断薬(CNQX)を局所注入した。注入後,約4時間の間,輻輳運動の増強は抑制され,その後次第に通常の増強レベルに戻った。この結果はLS皮質輻輳運動領域への視覚性入力が遮断されたためと考えられた。(3)グルタミン酸NMDA型受容体遮断薬(D-AP5)を局所注入し,30-60分後に視覚・脳内組み合せ刺激を行うと,輻輳運動の長期的増強は誘発されなかった。注入の前々日,及び翌々日に行なった遮断薬注入なしの対照実験では増強がみられた。この結果は視覚・脳内組み合せ刺激による輻輳運動増強に,LS皮質内の神経回路が関与することを示唆する。3.以上の結果は,大脳LS皮質の異なる微小分野が近見反応の制御に異なる役割を果たすという従来の研究で得られた仮説を支持する。

In this study, in the near future, in the field of LS (PMLS field), the results of this study were analyzed. Please make sure that you are close to each other and that you will be able to use the phone. The 1.LS skin (PMLS field) is broken by the camera center in the field of film production, the amplitude of the motion is less than the speed, and the components of the left and right eyes are not known as the camera. At the end of the first month, the amplitude and speed of the motor were reduced, and the left and right eyes were symmetrical. According to the results of the test, the normal sexual activity, the PMLS wild tail, is necessary, and the machine is able to send a message on behalf of the operator. In the former, there is no difference between the left and right sides of the PMLS wild kiss part, and the tail part is called the left and right side. (2. 1) close to the field of PMLS in the field of sports activities, small stimuli in the field are returned and returned (55 minutes, 20 minutes). After that, after a few days of training, there will be an increase in the amplitude and speed of the train in order to increase the speed of the train. (2) after the exercise has been verified, the PMLS skin should be injected into the NMDA capacitor occlusion device (CNQX). After injection, about 4 hours after the injection, the activity was used to strengthen the suppression activity, and the next step was usually to enhance the training performance. The results show that the LS skin information system is used in the field of health care, and the sexual input force is very important. (3) after 30-60 minutes after the injection of NMDA-type capacitor (D-AP5), the internal tissue was combined to stimulate the operation, and the long-term response was strengthened. The day before the injection, and the day before the injection, the day before the injection, and the day before the injection, the day before the injection, and the day before the injection, and the day before the injection, the day before the injection, and the day before the injection, the day before the injection, and the day before the injection. Results the results showed that the combination of stimuli and stimuli in the system showed that the activity was enhanced, and the neural circuits in the LS skin showed that they were instigated. 3. As a result of the above results, there is a close relationship between the control and control of LS. The results show that the results of the above results show that there is a lot of support for the study.