Synthesis and Preparation of Smart Membrane

智能膜的合成与制备

• 批准号: 13133204
• 负责人: SANUI Kohei
• 金额: $ 45.95万
• 依托单位: Sophia University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research on Priority Areas
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2004
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-13133204/
• 关键词: Smart membrane; Molecular cavity; Optical resolution; Cell-refinement; Self-assembly method; Proton transport membrane; Cyclo-imide compound; 固定化DNA膜; 細胞分離多孔膜; 高プロトン伝導性膜; シークウエンシャル高分子薄膜; 燃料電池; 高プロトン伝導膜; DNA; 光学活性基; チャネル機構; 選択分離膜; 光学異性体

To develop the novel smart membranes with high performance molecular cavities, some polymeric membranes are designated, synthesized, and prepared. The results below summary were obtained.(1) The cellulose-based membranes conjugated with DNAs were prepared. The membrane with large pore diameter showed preferential permeability of L-type amino acid, in contrast to case of small diameter membrane showing that of D-Type one. Furthermore, the introduction platinum complex to the chitosan membrane increases the amounts of DNA, and exhibited also preferential permeability of L-type amino acid In conclusion, these were channel type and optical resolution membranes as well as the cell membranes On the other hand, the polyurethane foam (PU) membranes introduced carboxylic acid groups were prepared to get a good cell-refinement membranes, the recovery factor of hematogenous cells was reached to 75% Especially, the surface-modified PU membrane with hyaluronic acid was highly separated the cells.(2 … More ) Monomer and/or the oligomer could be controllably layered by the "self-assembly method", it succeeded in manufacturing the fine membrane where molecular chains were arrangement to film thickness direction. The technique which makes the molecular cavities arranged regularly to film thickness direction could be established. On the one hand, the results of analyzing the cluster structure of the water in the new-created membrane for the proton transport, which was modified with the butane sulfonated polybenzoimidazole, the water molecule dispersed to the whole membrane.(3) In order to develop the high-performance separation-membrane having well-designed molecular cavities with collaboration of Group C, the molecular structures were simulated and designed by computer simulations, and the synthesis of cyclo-imide compounds was attempted. It succeeded in production of the composite membrane of cyclo-imides and the some polymers. The composite membrane obtained with the tetramer cyclo-imides, benzene was separated selectively. The structural analyses were performed by cooperation of Group B. Less

为了开发具有高性能分子空穴的新型智能膜，设计、合成和制备了一些聚合物膜。获得了以下总结结果。(1)制备了与DNA偶联的纤维素基膜。大孔径膜对L型氨基酸的渗透性优于小孔径膜对D型氨基酸的渗透性。此外，在壳聚糖膜上引入铂络合物，增加了DNA的含量，并表现出对L-型氨基酸的优先渗透性。总之，这些膜是通道型和光学分辨膜，也是细胞膜。另一方面，制备了引入羧酸基团的聚氨酯泡沫（PU）膜，以获得良好的细胞细化膜，对造血细胞的回收率达到75%，特别是透明质酸表面修饰的PU膜对造血细胞的分离效果更好。（二） ...更多信息 ）通过“自组装法”可控制地将聚乙二醇和/或低聚物分层，成功地制造了分子链沿膜厚度方向排列的精细膜。建立了使分子空穴沿膜厚方向规则排列的技术。一方面，分析了丁烷磺化聚苯并咪唑改性后的质子传输膜中水的团簇结构，水分子分散在整个膜中。(3)为了开发具有精心设计的分子空腔的高性能分离膜，与C组合作，通过计算机模拟对分子结构进行模拟和设计，并尝试合成环酰亚胺类化合物。成功地制备了环酰亚胺与某些聚合物的复合膜。用四聚体环酰亚胺制备的复合膜对苯进行了选择性分离。结构分析由B组合作进行。少

项目成果

Crystal structure and optical properties of CioHioN2PbBr4 and CioH22N2PbBr4

CioHioN2PbBr4 和 CioH22N2PbBr4 的晶体结构和光学性质

• 发表时间: 2002
• 期刊: Mol. Cryst. Liq. Cryst. 376
• 作者: Mitsuyasu Kawahara;Kenjiro Teshima;Masahiro Rikukawa;Kohei Sanui
• 通讯作者: Kohei Sanui

Heat-resistance and electrolyte materials of hydrocarbons(炭化水素系高耐熱電解質材料)

碳氢化合物耐热及电解质材料

• 发表时间: 2002
• 期刊: Industrial Materials(工業材料) 50
• 作者: R. Nakayama;Y. Shimono;M.Rikukawa
• 通讯作者: M.Rikukawa

The roles and new developments of artificial membranes on regenerative medical care(再生医療における人工膜 の役割と新展開)

人工膜在再生医疗中的作用及新进展

• 发表时间: 2002
• 期刊: Membrane(膜) 27(1)
• 作者: S.Furui;H.Nakajima;A.Higuchi
• 通讯作者: A.Higuchi

Control of Poly(styrene) Particles Size by In-Situ Polymerization

通过原位聚合控制聚苯乙烯粒径

• 发表时间: 2001
• 期刊: Polymer Journal 33
• 作者: Shigeki Chujo;Masayoshi Rikukawa;Kohei Sanui;Naoya Ogata;Satoshi Koizumi;Takeji Hashimoto
• 通讯作者: Takeji Hashimoto

最先端の機能膜技術-未来の膜技術を展望する-

前沿功能膜技术-展望未来膜技术-

• 发表时间: 2005
• 作者: Y. Iwasaki;et al (CP-PACS collaboration);樋口亜紺(分担執筆)
• 通讯作者: 樋口亜紺(分担執筆)