Emotion regulation variability and flexibility across the eating disorder spectrum

整个饮食失调谱系中情绪调节的变异性和灵活性

• 批准号: 502010784
• 负责人: Professor Dr. Stefan Ehrlich, Ph.D.
• 金额: --
• 依托单位: Bereich Psychosoziale Medizin und Entwicklungsneurowissenschaften
• 依托单位国家: 德国
• 项目类别: Research Grants
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/502010784?language=en
• 关键词: Emotion; regulation; variability; flexibility; across

Individuals with eating disorder (ED) symptoms including those with full-syndrome EDs such as Anorexia nervosa (AN) Bulimia nervosa (BN) or Binge-eating disorder (BED) self-report limited access to adaptive emotion regulation (ER) strategies. Instead, they frequently employ ER strategies (e.g. rumination) that are considered to have only short-lasting effects and are associated with negative consequences. However, experimental evidence is scarce and the few existing studies have delivered mixed results. Nonetheless, some findings including our own give rise to the novel assumption that there might not be a general deficit in executing more effective ER strategies per se, but rather that individuals with ED symptoms might have difficulties related to the flexible context-dependent selection of the right strategies in the right moment. Newer models of ER haveincorporated a more dynamic approach by suggesting that successful ER might be related to 1. ER variability (e.g. the size of the strategy repertoire), 2. sensitivity to contextual changes and 3. ER flexibility, the covariation of the two. The proposed project will investigate each of these concepts, in both patients with EDs (AN and BN/BED syndrome using a laboratory assessment), as well as subclinical individuals with increased ED symptoms (dimensional approach using an online platform). Aim 1 investigates whether ER deficits are related to reduced ER variability. To this end, we apply ecological momentary assessment (via smartphones) to investigate the number of different ER strategies applied in real life. Aim 2 addresses sensitivity to contextual factors that have recently been shown to influence ER strategy choice in healthy individuals using an established ER strategy choice paradigm. To investigate influences of different stimulus characteristics (such as high/low negative intensity, or high/low caloric food) on strategy choice, the laboratory assessment not only includes strategy choice, but also objective measures of emotional reactivity and ER choice as well as success (pupil dilation and fMRI including MVPA). Influences of perceived effort and goalmanipulation on ER strategy choice will be assessed using adaptions of the same task in a large crowdsourced online sample. Aim 3 combines the data of Aim 1 and 2. Analyses will focus on a) whether there are associations between ER flexibility (covariation between ER variability and context changes) and ED symptoms or groups and b) whether ER variability and flexibility are associated with short- and long term success of applied strategies. The 3 aims of the proposed project promise to deliver a better understanding and more finegrained description of the apparent ER deficit in EDs as well as individuals with ED symptoms which can be used to develop new treatment approaches and preventative measures.

患有进食障碍（艾德）症状的个体，包括那些患有完全综合征的ED的个体，如神经性厌食症（AN）、神经性贪食症（BN）或暴食症（B艾德），自我报告获得适应性情绪调节（ER）策略的机会有限。相反，他们经常采用ER策略（例如反刍），这些策略被认为只有短暂的影响，并与负面后果有关。然而，实验证据是稀缺的，现有的几项研究已经提供了混合的结果。尽管如此，包括我们自己在内的一些研究结果提出了一个新的假设，即在执行更有效的ER策略本身方面可能并不存在普遍缺陷，而是患有艾德症状的个体可能在正确的时间选择正确的策略时遇到了与灵活的上下文相关的困难。较新的ER模型采用了一种更动态的方法，表明成功的ER可能与1有关。ER可变性（例如，策略库的大小），2.对环境变化的敏感性和3. ER灵活性，两者的协变。拟议项目将在ED患者（使用实验室评估的AN和BN/B艾德综合征）以及艾德症状增加的亚临床个体（使用在线平台的维度方法）中研究这些概念中的每一个。目的1研究ER缺陷是否与ER变异性降低有关。为此，我们应用生态瞬时评估（通过智能手机），以调查在真实的生活中应用的不同ER策略的数量。目的2地址的敏感性，最近已被证明影响ER策略选择健康个体使用一个既定的ER策略选择范式的上下文因素。为了研究不同刺激特征（如高/低负强度或高/低热量食物）对策略选择的影响，实验室评估不仅包括策略选择，还包括情绪反应性和ER选择以及成功（瞳孔扩张和功能MRI，包括MVPA）的客观测量。感知努力和目标操纵对ER策略选择的影响将使用大型众包在线样本中相同任务的适应来评估。目标3结合了目标1和目标2的数据。分析将侧重于a）ER灵活性（ER变异性和环境变化之间的协变）与艾德症状或组之间是否存在关联，以及B）ER变异性和灵活性是否与所应用策略的短期和长期成功相关。拟议项目的3个目标承诺提供更好的理解和更精细的描述ED中的明显ER缺陷以及具有艾德症状的个体，可用于开发新的治疗方法和预防措施。