Investigation of novel molecular targeted therapeutics based on epigenetics in colorectal cancer.

基于表观遗传学的结直肠癌新型分子靶向治疗的研究。

• 批准号: 16K19943
• 负责人: TOKUNAGA Ryuma
• 金额: $ 2.5万
• 依托单位: Kumamoto University (2017-2018)Japanese Foundation for Cancer Research (2016)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2016
• 资助国家: 日本
• 起止时间: 2016-04-01 至 2019-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-16K19943/
• 关键词: 大腸癌; マイクロRNA; 細胞周期; 血管新生; 上皮間葉転換; 化学療法; JMJD3; エピジェネティクス; EZH2

项目成果

Laparoscopic resection of a tumour in the ischiorectal fossa - a video vignette.

腹腔镜切除坐骨直肠窝肿瘤 - 视频小插图。

• DOI: 10.1111/codi.13806
• 发表时间: 2017
• 期刊: Colorectal Dis
• 影响因子: 3.4
• 作者: Tokunaga R;Akiyoshi T;Hiyoshi Y;Fukunaga Y;Ueno M
• 通讯作者: Ueno M

Colorectal cancer: epigenetic alterations and their clinical implications.

• DOI: 10.1016/j.bbcan.2017.09.003
• 发表时间: 2017-12
• 期刊: Biochimica et biophysica acta. Reviews on cancer
• 作者: Puccini A;Berger MD;Naseem M;Tokunaga R;Battaglin F;Cao S;Hanna DL;McSkane M;Soni S;Zhang W;Lenz HJ
• 通讯作者: Lenz HJ

Cancer-related multiple brain infarctions caused by Trousseau syndrome in a patient with metastatic colon cancer: a case report.

• DOI: 10.1186/s40792-016-0217-7
• 发表时间: 2016-12
• 期刊: Surgical case reports
• 影响因子: 0.8
• 作者: Akiyama T;Miyamoto Y;Sakamoto Y;Tokunaga R;Kosumi K;Shigaki H;Kurashige J;Iwatsuki M;Baba Y;Yoshida N;Baba H
• 通讯作者: Baba H

Incidence and risk factors of synchronous colorectal cancer in patients with esophageal cancer: an analysis of 480 consecutive colonoscopies before surgery

食管癌患者同步性结直肠癌的发病率及危险因素：480例术前连续结肠镜检查分析

• DOI: 10.1007/s10147-016-1015-8
• 发表时间: 2016
• 期刊: Int J Clin Oncol
• 影响因子: 3.3
• 作者: Yoshida N;Tamaoki Y;Baba Y;Sakamoto Y;Miyamoto Y;Iwatsuki M;Shono T;Miyamoto H;Imuta M;Kurashige J;Sawayama H;Tokunaga R;Watanabe M;Sasaki Y;Yamashita Y;Baba H.
• 通讯作者: Baba H.

Prognostic and clinical impact of PIK3CA mutation in gastric cancer: pyrosequencing technology and literature review.

• DOI: 10.1186/s12885-016-2422-y
• 发表时间: 2016-07-07
• 期刊: BMC cancer
• 影响因子: 3.8
• 作者: Harada K;Baba Y;Shigaki H;Ishimoto T;Miyake K;Kosumi K;Tokunaga R;Izumi D;Ohuchi M;Nakamura K;Kiyozumi Y;Kurashige J;Iwatsuki M;Miyamoto Y;Sakamoto Y;Yoshida N;Watanabe M;Baba H
• 通讯作者: Baba H