Novel adjuvant method of malignant brain tumor neutron capture therapy with absorbed dose evaluation and tumor localization using composite boron and high-Z element nanoparticles.

使用复合硼和高Z元素纳米颗粒进行吸收剂量评估和肿瘤定位的恶性脑肿瘤中子俘获治疗的新辅助方法。

• 批准号: 17K15797
• 负责人: ZABORONOK ALEXANDER
• 金额: $ 1.91万
• 依托单位: University of Tsukuba
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2017
• 资助国家: 日本
• 起止时间: 2017-04-01 至 2019-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-17K15797/
• 关键词: glioma; nanoparticles; radiotherapy; radiodiagnosis; BNCT; boron; high-Z element

项目成果

Boron neutron capture therapy for malignant brain tumors: current situation in the world, our experience in Russia and Japan, and further development perspectives.

硼中子俘获治疗恶性脑肿瘤：世界现状、俄罗斯和日本的经验及进一步发展前景。

• 发表时间: 2018
• 作者: Zaboronok A;Ishikawa E;Taskaev S;Bykov T;Kasatov D;Kolesnikov I;Koshkarev A;Makarov I;Shchudlo I;Volkova O;Mechetina L;Taranin A;Zavjalov E;Akulov A;Kanygin V;Kasatova A;Kichigin A;Byvaltsev V;Sato E;Nakai K;Mathis BJ;Yamamoto T;Mats
• 通讯作者: Mats

Boron nanoparticles production by ultrasonic cavitation.

通过超声波空化生产硼纳米粒子。

• 发表时间: 2018
• 作者: Uspenskii S;Khaptakhanova P;Kurkin T;Zaboronok A;Zelenetskii A;Selyanin M;Taskaev S.
• 通讯作者: Taskaev S.

Hybrid gold and boron nanoparticles for treatment and boron dose estimation in boron neutron capture therapy for malignant glioma

混合金和硼纳米粒子用于恶性神经胶质瘤硼中子捕获治疗中的治疗和硼剂量估计

• 发表时间: 2018
• 作者: Alexander Zaboronok;Sergey Taskaev;Vladimir Kanygin;Timofei Bykov;Kazutaka Mitsuishi;Eisuke Sato;Kei Nakai,Takao Tsurubuchi;Fumiyo Yoshida;Eiichi Ishikawa;Bryan J. Mathis;Tetsuya Yamamoto,Akira Matsumura
• 通讯作者: Tetsuya Yamamoto,Akira Matsumura

Perspectives of combined photodynamic diagnosis and accelerator-based neutron capture therapy of malignant glioma using photosensitizer- and 10B-containing liposomes.

使用含光敏剂和 10B 的脂质体对恶性神经胶质瘤进行光动力诊断和基于加速器的中子捕获联合治疗的前景。

• 发表时间: 2017
• 作者: Zaboronok A;Taskaev S;Muhamadiyarov R;Kichigin A;Volkova O;Mechetina L;Sato E;Nakai K;Yamamoto T;Taranin A;Kanygin V;Mathis BJ;Matsumura A.
• 通讯作者: Matsumura A.

Accelerator-based boron neutron capture therapy for malignant glioma using composite boron-gold nanoparticles: preclinical evaluation.

使用复合硼-金纳米颗粒的基于加速器的硼中子捕获疗法治疗恶性神经胶质瘤：临床前评估。

• 发表时间: 2018
• 作者: Zaboronok A;Taskaev S;Volkova O;Mechetina L;Taranin A;Kanygin V;Zelenetskii A;Uspenskii S;Khaptakhanova P;Ishikawa E;Nakai K;Yamamoto T;Mathis BJ;Tsurubuchi T;Matsumura A.
• 通讯作者: Matsumura A.