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Molecular immunopathology of human cancer stem cell

Molecular immunopathology of human cancer stem cell
人类癌症干细胞的分子免疫病理学
批准号：
21249025
负责人：
SATO Noriyuki
金额：
$29.45万
依托单位：
Sapporo Medical University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (A)
财政年份：
2009
资助国家：
日本
项目状态：
已结题
起止时间：
2009 至 2011
来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-21249025/
关键词：
分子病理癌幹細胞腫瘍抗原CTL癌免疫分子標的SP法CSC/CICCSCCIC

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中文摘要
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英文摘要
This study was aimed to analyze molecular pathological nature of human cancer stem cell(CSC)/cancer-initiating cell(CIC). Particularly we studied molecules expressed specifically in CSC/CIC and their immunological characteristics. Consequently we successfully identified such interesting antigens. These antigens have molecular features of cancer-testis antigens, and could work as potential immunogenic molecule in human cancers.
期刊论文(77)
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科研奖励(0)
会议论文
Immunosuppressive effect on T cell activation by interleukin-16- and interleukin-10-cDNA-double-transfected human squamous cell line.
白细胞介素 16 和白细胞介素 10 cDNA 双转染人鳞状细胞系对 T 细胞活化的免疫抑制作用。
DOI： 10.1016/j.burns.2008.06.017
发表时间： 2009
期刊： Burns : journal of the International Society for Burn Injuries
影响因子： --
作者： [Yoshitaka Matsumoto, T. Fujita, I. Hirai, H. Sahara, T. Torigoe, K. Ezoe, T. Saito, W. Cruikshank, T. Yotsuyanagi, N. Sato]
通讯作者： N. Sato
Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population
DOI： 10.1016/j.yexmp.2011.09.016
发表时间： 2012-02-01
期刊： EXPERIMENTAL AND MOLECULAR PATHOLOGY
影响因子： 3.6
作者： [Mori, Takashi, Nishizawa, Satoshi, Sato, Noriyuki]
通讯作者： Sato, Noriyuki
The feasibility of Cep55/c10orf3 derived peptide vaccine therapy for colorectal carcinoma
DOI： 10.1016/j.yexmp.2010.10.001
发表时间： 2011-02-01
期刊： EXPERIMENTAL AND MOLECULAR PATHOLOGY
影响因子： 3.6
作者： [Inoda, Satoko, Morita, Rena, Sato, Noriyuki]
通讯作者： Sato, Noriyuki
Spatiotemporal Regulation of Heat Shock Protein 90-Chaperoned Self-DNA and CpG-Oligodeoxynucleotide for Type I IFN Induction via Targeting to Static Early Endosome
DOI： 10.4049/jimmunol.1000490
发表时间： 2010-06-15
期刊： JOURNAL OF IMMUNOLOGY
影响因子： 4.4
作者： [Okuya, Koichi, Tamura, Yasuaki, Sato, Noriyuki]
通讯作者： Sato, Noriyuki
共 58 条
    Extracellular Hsp90 plays a pivotal role in innate immunity and adaptive immunity
    • 批准号：
      24659165
    • 项目类别：
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额：
      $2.5万
    • 财政年份：
      2012
    • 负责人：
      SATO Noriyuki
    • 依托单位：
      Sapporo Medical University
    A study on the economic structure of Mongolia in the Qing era from the viewpoint of the Chinese commercial district "Mai-mai-cheng"
    • 批准号：
      23720341
    • 项目类别：
      Grant-in-Aid for Young Scientists (B)
    • 资助金额：
      $2.75万
    • 财政年份：
      2011
    • 负责人：
      SATO Noriyuki
    • 依托单位：
      Tohoku University
    patho-physiologic role of HSP90 in the aseptic inflammatory process
    • 批准号：
      22659075
    • 项目类别：
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额：
      $1.98万
    • 财政年份：
      2010
    • 负责人：
      SATO Noriyuki
    • 依托单位：
      Sapporo Medical University
    Development of therapeutic cancer vaccine
    • 批准号：
      17016061
    • 项目类别：
      Grant-in-Aid for Scientific Research on Priority Areas
    • 资助金额：
      $29.57万
    • 财政年份：
      2005
    • 负责人：
      SATO Noriyuki
    • 依托单位：
      Sapporo Medical University
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