Study to identify viral genomic factors for severe dengue virus infections in Asia and Africa
Study to identify viral genomic factors for severe dengue virus infections in Asia and Africa
批准号:
21256004
负责人:
MORITA Kouichi
金额:
$29.62万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
To identify viral genomic factors for severe dengue virus infections, we conducted field surveys in Asia and Africa. A number of severe dengue cases were confirmed among adult patients with primary infections, suggesting additional mechanism of severity on top of the antibody-dependent infection theory. Viral quasispecies were analyzed and showed different target cell tropism even with a single amino acid alternation on E-protein.
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Isolation and characterization of two phenotypically distinct dengue type-2 viruses from the same dengue hemorrhagic fever patients.,
来自同一登革出血热患者的两种表型不同的登革热 2 型病毒的分离和表征。
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Pham, C. T, Daisuke Ishii, Morita K]
通讯作者:
Morita K
Dengue virus type 2 recognizes the carbohydrate moiety of neutral glycosphingolipids in mammalian and mosquito cells
2 型登革热病毒识别哺乳动物和蚊子细胞中中性鞘糖脂的碳水化合物部分
DOI:
--
发表时间:
2011
期刊:
Microbiol Immunol.
影响因子:
--
作者:
[Wichit S, Morita K(9番目), (他10名), Jampangern W]
通讯作者:
Jampangern W
ウイルスの今日的意義・11.アルボウイルス
病毒在当今的意义 11. 虫媒病毒
DOI:
--
发表时间:
2011
期刊:
化学療法の領域
影响因子:
--
作者:
[森田公一, 岡本健太]
通讯作者:
岡本健太
Isolation and characterization of two phenotypically distinct dengue type-2 virus isolates from the same dengue hemorrhagic Fever patient
从同一登革出血热患者中分离出两种表型不同的登革热 2 型病毒并对其进行鉴定
DOI:
--
发表时间:
2009
期刊:
Jpn J Infect Dis
影响因子:
2.2
作者:
[Kinoshita H, Mathenge EG, Hung NT, Huong VT, Kumatori A, Yu F, Parquet MC, Inoue S, Matias RR, Natividad FF, Morita K, Hasebe F]
通讯作者:
Hasebe F
赤芽球細胞への株特異的デングウイルス感染と感受性受容体の同定
红系细胞的株特异性登革热病毒感染及易感受体的鉴定
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Takayoshi Yamaguchi, Sonam Ngodup, Mitsuhiro Nose, Shinya Takeda, 山口 進康,他, 亀田貴之,安積愛理,福島杏希,唐 寧,松木 篤,鳥羽 陽,早川和一, 岡本健太]
通讯作者:
岡本健太
共 52 条
Urgent research on COVID-19 utilizing infectious disease research stations in Asia
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批准号:19K24679
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项目类别:Grant-in-Aid for Special Purposes
-
资助金额:$41.6万
-
财政年份:2020
-
负责人:MORITA Kouichi
-
依托单位:
Comprehensive survey of arboviruses in the tropics
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批准号:25305015
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.15万
-
财政年份:2013
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负责人:MORITA Kouichi
-
依托单位:
Genetic variation of dengue virus genomes associated with severity of dengue hemorrhagic fever
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批准号:18406017
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.28万
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财政年份:2006
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负责人:MORITA Kouichi
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依托单位:
Molecular and viral research on dengue hemorrhagic fever
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批准号:15406020
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$6.4万
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财政年份:2003
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负责人:MORITA Kouichi
-
依托单位:
Survey for the cause of emerging dengue haemorrhagic fever in Southeast Asia
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批准号:13576016
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$5.76万
-
财政年份:2001
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负责人:MORITA Kouichi
-
依托单位:
海外基金