Activation of catalyzed-liquid phase reactions in a microreactor by acoustic wave resonance oscillation

声波共振振荡激活微反应器中的催化液相反应

• 批准号: 23246137
• 负责人: INOUE Yasunobu
• 金额: $ 31.62万
• 依托单位: Nagaoka University of Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (A)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-23246137/
• 关键词: 触媒・化学プロセス; 表面・界面物性; マイクロリアクター; 圧電効果; 共鳴振動; 固定化酵素; 液総触媒反応; 強誘電体; ガラクトースオキシダーゼ; アミノ酸オキシダーゼ; ミカエリスメンテン定数; 触媒化学プロセス; 表面界面物性; 酵素反応; 液相触媒反応; 固定化酵素触媒; 酸触媒

In aiming at establishing a method for the activation of catalyzed liquid-phase reactions, the acoustic wave resonance oscillation that can be generated on a ferroelectric crystal by rf electric power was applied to the catalytic reactions in a microreactor by the immobilized enzymes. In all the immobilized enzymes such as glucose oxidase, galactose oxidase, D- and L-amino acid oxidase, the remarkable catalytic activity enhancement was induced by the generation of resonance oscillation with considerable decreases in the activation energy of the reactions. The resonance oscillation was revealed to have the significant effects of strengthening the interactions between the enzymes and substrates, and it was concluded that the resonance oscillation is quite useful to activate the immobilized catalysts for liquid phase reactions.

为了建立一种激活液相催化反应的方法，将射频电功率在铁电晶体上产生的声波共振振荡应用于微反应器中固定化酶的催化反应。在所有的固定化酶，如葡萄糖氧化酶，半乳糖氧化酶，D-和L-氨基酸氧化酶，显着的催化活性增强诱导的共振振荡的产生，显着降低反应的活化能。结果表明，共振振荡对酶与底物的相互作用有明显的增强作用，对固定化催化剂的活化具有重要意义。

项目成果

Effects of acoustic wave resonance oscillation on immobilized enzyme

• DOI: 10.1016/j.apsusc.2013.12.016
• 发表时间: 2014-03
• 期刊: Applied Surface Science
• 影响因子: 6.7
• 作者: H. Nishiyama;Tomoya Watanabe;Y. Inoue

Activation of immobilized glucose oxidase enzyme by acoustic wave resonance oscillation

声波共振振荡激活固定化葡萄糖氧化酶

• DOI: 10.1246/cl.131218
• 发表时间: 2014
• 期刊: Chem. Lett.
• 作者: Hiroshi Nishiyama;Masayuki Kazui;Yasunobu Inoue
• 通讯作者: Yasunobu Inoue

Activation of scandium(III) triflate catalyst coordinated on surface for aldol condensation by acoustic wave effects

声波效应活化表面配位三氟甲磺酸钪催化剂羟醛缩合

• 发表时间: 2013
• 作者: Hiroshi Nishiyama;Ryuusuke Asari;Yasunobu Inoue
• 通讯作者: Yasunobu Inoue

Acoustic wave excitation of catalysis at surfaces

表面催化的声波激发

• 发表时间: 2013
• 作者: H. Nishiyama;T. Watanabe;Y. Inoue;白石一馬，眞山 剛，山崎倫昭，河村能人;井上泰宣・西山洋・渡邉智也;Kouji Yasuda;本浪雅史，萩原幸司，伊津野仁史，中野真由，山崎倫昭，眞山 剛，河村能人;(Yasunobu Inoue)
• 通讯作者: (Yasunobu Inoue)

Effects of acoustic wave resonance oscillation on catalysis of immobilized glucose oxidase enzyme for glucose oxidation in a microreactor

声波共振振荡对微反应器中固定化葡萄糖氧化酶催化葡萄糖氧化的影响

• 发表时间: 2011
• 作者: T. Watanabe,M. Kazui,H. Nishiyama;H. Matsubara;Y. Inoue
• 通讯作者: Y. Inoue