Activation of catalyzed-liquid phase reactions in a microreactor by acoustic wave resonance oscillation

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In aiming at establishing a method for the activation of catalyzed liquid-phase reactions, the acoustic wave resonance oscillation that can be generated on a ferroelectric crystal by rf electric power was applied to the catalytic reactions in a microreactor by the immobilized enzymes. In all the immobilized enzymes such as glucose oxidase, galactose oxidase, D- and L-amino acid oxidase, the remarkable catalytic activity enhancement was induced by the generation of resonance oscillation with considerable decreases in the activation energy of the reactions. The resonance oscillation was revealed to have the significant effects of strengthening the interactions between the enzymes and substrates, and it was concluded that the resonance oscillation is quite useful to activate the immobilized catalysts for liquid phase reactions.