Development of a wearable pneumatic artificial heart system

研制了一种气动心室辅助装置(PVAD)和全人工心脏(PTAH)。配备2节电池的驱动器的大小和重量分别为250x110x210 mm和4.3公斤。在溢流型循环模拟实验和动物实验中对PVAD和Ptah的性能进行了检测。在循环模拟试验中，VAD的平均泵流量为3.4~6.7 L/min，平均电耗为8.0~19.7W。在循环模拟中，电池的最长放电时间为7小时38分钟。在小牛慢性动物实验中也对VAD进行了检测。小牛存活28天，大体状况良好。旁路流量和电能消耗分别维持在4.1/-0.4 L/min和13.3/-0.4W。在小牛急性动物实验中，对使用2驱动器的Ptah进行了评估。平均泵流量为3.9~5.4 L/min，平均电耗为5.3~17.6W。

A pneumatic ventricular assist device (PVAD) and total artificial heart (PTAH) were developed. The size and weight of the driver with the 2 battery are 250x110 x210 mm and 4.3 kg. The performance of the PVAD and PTAH were examined in an overflow type circulation mock and animal tests. The VAD achieved the mean pump flow ranging from 3.4 to 6.7 L/min and the mean electric power consumption ranging from 8.0 to 19.7 W in the circulation mock test. The longest electric discharge of the battery of 7 hours and 38 minutes was possible in the circulation mock. The VAD was also examiend in the chronic animal test using calf. The calf survived for 28 days in good general condition. The bypass flow and the electric power consumption were maintained at 4.1+/-0.4 L/min and 13.3+/-0.4 W. The PTAH using the 2 driver was evaluated in the acute animal test using calf. The mean pump flow ranging from 3.9 to 5.4 L/min and the mean electric power consumption ranging from 5.3 to 17.6 W were achieved.