Neuroscience of Music

20世纪90年代初，日本文部科学省（MECSST）启动了“卓越中心（COE）”计划，其主要目的是重点支持那些被认为有能力发展成为世界级研究中心的优秀研究团体（Science 269：474，1995）。因此，为特遣队所属装备项目挑选的项目领导人不仅负责执行常规研究项目，而且负责在其指导下建立一个研究所。“音乐的神经科学”项目成功地创建了这样一个世界级的人类脑科学研究所。其主要目的是基于各种最先进的非侵入性成像先进技术对“人类思维”进行科学描述。一个代表性的硬件开发是独特的3.0T垂直人体MRI系统。在虚拟现实环境下，该系统，获得了2000年的技术奖，从社会的Ins ...更多信息 仪器与控制工程（SICE），正在产生大量不可或缺的数据，作为世界上唯一能够在“真正”生理条件下提供大脑功能的系统。该项目开发的新算法的代表性例子是轴突和神经元成像。通过更高分辨率的成像方法，该算法在亚微米级提供了显著高的解剖分辨率。独立成分-交叉相关-序贯历元（ICS）分析方法，在这个项目中开发的，基于高阶统计量，已成功地提高了非侵入性皮质分析的能力，相当于针研究在非人灵长类动物的水平。“真正的”显微镜目前正在开发7.0T人体系统。利用超级计算机上的k空间统计数据的实时功能性磁共振成像也即将完成。对各项调查的详细描述超出了本摘要的范围。原则上，研究的重点是阐明人类特有的大脑功能，如语言，抽象思维或惯用手的大脑功能组织。为了寻找大脑高级功能的基本主体单位，建立了“自组织联想记忆”概念，称为“大脑漩涡理论”，并发展成为新的项目“水分子神经科学”，其主要目标是科学地证明这一理论。少

The main objective of the "Center of Excellence (COE)" project launched by the Japanese Ministry of Education, Culture, Science, Sports, and Technology (MECSST) in the early 1990's was to provide focused support to super select research groups deemed capable of developing into world-class research centers (Science 269:474, 1995). Accordingly, the project leaders selected for COE projects were responsible not only for carrying out conventional research projects but also for establishing an institute under his/her guidance. This program "Neuroscience of Music" has successfully created such a world-class institute in the field of human brain science. Its major aim is the scientific description of the "human mind" based on various state-of-the-art, advanced technologies in non-invasive imaging. A representative hardware development is the unique 3.0T vertical human MRI system. Under a virtual reality environment, this system, which received the 2000 Technology Award from the Society of Ins … More trument and Control Engineering (SICE), is producing a large number of indispensable data as the only system in the world capable of providing brain functionality under "truly" physiological conditions. Representative examples of new algorithms developed by this project are axonal and neuronal imaging. With the higher resolution imaging method, this algorithm has provided significantly high anatomical resolution at the sub-micron level. The Independent component-Cross correlation-Sequential epoch (ICS) analysis method developed in this project, based on higher order statistics, has successfully increased the capability of non-invasive cortical analysis at a level equivalent to needle studies in non-human primate. "True" microscopy is now under development with the 7.0T human system. Real-time functional MRI is also near completion, making use of k-space statistics on supercomputers. A detailed description of the individual investigations is above the scope of this summary. In principle, studies are focused on the elucidation of brain functional organization of human-specific brain functions such as language, abstract thinking, or handedness. Efforts in search for the basic principal unit of higher brain function have forged the establishment of "self-organizing associative memory" concept, referred to as "Vortex Theory of the Brain", and evolved into the new project "Neuroscience of Water Molecule" the main objective of which is to scientifically prove this theory. Less