Design and Control of Advanced Molecular Assembly Systems

在这个项目中，我们首先建立了基于两个指导原则的组装和组织分子的策略，即当设计得当时，分子可以选择性地相互吸引或排斥，并且结构的维度在控制分子组装的性质和功能方面最有用。然后，我们设计的分子，具有表现出弱的分子间相互作用，如配位键，氢键，疏水相互作用，分散力，交换相互作用等的品种，数量，位置和矢量的功能基团将定制的大小和形状的分子组装。在合成所设计的组分分子之后，它们的组装和组织已经通过以下方式进行：1。自组装，2。晶体学技术，3.单层/双层方法，4.通过扫描探针显微镜进行分子操作。这些方法不仅适用于 关于我们 由于在这些介观尺度的有序分子组装体中，机械、光学、电子、磁性和化学相互作用预计是定向的和各向异性的，因此将产生以下从未通过天然分子组装体获得的分子功能和功能分子材料。一维材料：模拟DNA的双螺旋信息存储，分子传感，高度有序的金属离子阵列催化剂，二维材料：在生物体中发现的形态的创建，使手性识别成为可能的界面，二维金属络合物三维材料：通过人工分子双层、有机沸石、分子光磁记录装置的倍增，我们相信，通过本项目所取得的研究成果将成为连接20世纪和21世纪的里程碑，为科学的新纪元打开一扇大门。少

In this project, we first established strategies for assembling and organizing molecules on the basis of two guiding principles that, when properly designed, molecules can attract or repel each other selectively, and that dimensionality of the structures is most instrumental in controlling the properties and functions of molecular assemblies. We then designed molecules that have the functional groups for exhibiting weak intermolecular interactions such as coordination bonds, hydrogen bonds, hydrophobic interactions, dispersion force, exchange interaction, etc. The varieties, numbers, locations and vectors of such groups will tailor the size and shape of the resulting molecular assemblies. After the synthesis of the designed component molecules, the assemblage and organization of them have been performed by : 1. Self-assembly, 2. crystallographic technology, 3. monolayer/bilayer methods, 4. molecular manipulation by scanning probe microscopy. These methods will be applied not only for s … More ingle components but also for two or more components.Since mechanical, optical, electronic, magnetic and chemical interactions are expected to be directional and anisotropic in these organized molecular assemblies of mesoscopic scale, the following molecular functions and functional molecular materials which have never been attained by assemblies of naive molecules will be produced. One-dimensional materials : Double-helix information storage mimicking DNA, molecular sensing, highly ordered metal-ion array catalysts, Two-dimensional materials : Creation of morphologies found in living organism, interfaces enabling chiral recognition, two-dimensional metal complexes Three-dimensional materials : Two-dimensional reaction environments by multiplication of artificial molecular bilayers, organic zeolites, molecular optomagnetic recording devices, transparent magnets.We believe that research achievements obtained through this Project will become a milestone linking the 20th century to the 21st century and open a door toward the new era of science. Less