Syntheses of Supramolecular Capsules with "On-off-type" Switch Functions

采用两种不同的方法合成了分子胶囊。第一种方法是连接半球形杯[n]芳烃的两个上边缘。由于分子内反应和分子间反应之间的竞争，这种方法相当困难。由两个杯[n]芳烃组成的胶囊分子对客体分子的亲和力增强。第二种方法是盖住或双桥接一个杯[n]芳烃。杯状[6]芳烃被1,3,5-三（溴乙基）苯盖上，得到一个具有封闭内腔的分子。杯状[8]芳烃与1,2-双（溴乙基）苯的双桥接也得到了一个胶囊分子。它们显示了客体离子和分子的动力学抑制交换。

Molecular capsules were synthesized by two different methods. The first method is to connect two upper edges of hemisphere-shaped calix [n] arenes. This methods were considerably difficult because of competition between intra-and intermolecular reactions. The capsule molecules composed of two calix [n] arenes show the enhanced affinity toward guest molecules. The second method is to cap or doubly-bridge one calix [n] arene. Capping of calix [6] arene with 1,3,5-tris (bromomethyl) benzene gave a molecule with a closed inner cavity. Double bridging of calix [8] arene with 1,2-bis (bromomethyl) benzene also gave a capsule molecule. They showed a kinetically suppressed exchange of guest ions and molecules.