Diversity of energy transducing mechanism by organella from the parasites such as Plasmodium

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Eukaryotic cells possess organella, which are essential for the maintenance of their biological function. By the extensive studies, many new findings on the origin, reaction mechanism and interaction of energy transducing mitochondria and plastid, which are indispensable for the survival of the cells, have been reported. Recent study revealed the unique mitochondria of parasites, which adapt to the anaerobic environment in the host as well as the parasites without mitochondria. However, information on the process of their establishment, details of their physiological functions, interaction between the organella is limited.The aim of this research project is to answer these questions and establish a base of our understanding the diversity of energy transduction in the novel organella, dynamic interaction between the organella and their evolution. In this study, by focusing on parasitic protozoas such as malaria parasite, we have found novel properties of parasite organella, which bring a new insight organella biology.