Adaptive Evolution of BRCA1 in Ancestral Mammals
Adaptive Evolution of BRCA1 in Ancestral Mammals
批准号:
DP0450066
负责人:
Prof Simon Easteal
金额:
$15.96万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2004
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2004-01-01 至 2006-12-31
中文摘要
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英文摘要
This project investigates adaptive evolution of BRCA1 in the early radiation of mammals. We will test the hypothesis that the evolution of mammary glands and X chromosome inactivation has resulted in modification of the BRCA1 protein sequence as it aquired new roles in these processes. We will also investigate the importance of these changes inducing compensatory changes in other parts of the protein.
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依托单位:
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