Genomic Basis of Resistance to Poisoning by Sodium Fluoroacetate (Compound 1080) in Australian Wildlife

在澳大利亚，价值数十亿美元的农业保护活动通过使用氟乙酸钠（1080）来保护害虫。目标物种是澳大利亚兔和狐狸以及新西兰刷尾负鼠。长期使用生物防治剂会引起遗传抗性。这在西澳大利亚州自然发生在生活在本地植物中1080水平高的地区的本地动物中。作为袋鼠基因组项目的一部分，我们的目标是发现这种抗性的基因组基础。其成果将是提高管理有害动物种群的能力和了解植物-动物相互作用的演变。

In Australia agricultural conservation activities worth billions of dollars are protected by using sodium fluoroacetate (1080) against pest animals. Target species are Australian rabbits and foxes and New Zealand brushtail possums. Prolonged use of biocontrol agents causes genetic resistance. This occurs naturally in Western Australia in native animals living in areas with high levels of 1080 in native plants. As part of the Kangaroo Genome project our aim is to discover the genomic basis of this resistance. The outcomes will be improved ability to manage pest animal populations and understanding of the evolution of plant-animal interactions.