Luminescent inorganic-organic hybrid particles for a combinatorial in-situ fluorescence detection of temperature and pH value (FL-Detect)

在混合材料领域，该项目的目标是无机-有机混合颗粒，这些颗粒表现出发光性，并根据温度和pH值显示出这种性质的变化。这应该允许温度及其变化的光学检测以及系统的pH值的检测和相应的变化作为单一的以及同时的分析。为了实现这一目标，根据两个研究小组的专业知识选择了具有广泛发光特性的混合材料：Feldmann组的无机-有机纳米颗粒（AOH-NP）和Müller-Buschbaum组的金属-有机框架（MOFs）和配位聚合物（CP）。将在各组中合成选定的化合物，研究所述检测选项并相应地表征。单个化合物可以在特定的温度和pH值范围内发生发光变化。基于荧光的检测来自不同的过程，例如热猝灭或例如，质子化/去质子化，并且可以导致发光强度的显著改变（“关闭/开启”）或发光色度的显著改变，从而能够进行“原位”检测。此外，来自这两个领域的合适候选物将被组合成甚至更复杂的杂化材料，以便协同地利用两种或更多种单一效应。这将导致可检测的温度和pH值范围较宽。总而言之，这两组化合物和材料的适当组合将用于实现荧光温度计以及发光pH纸。

In the field of hybrid materials, the project aims at inorganic-organic hybrid particles that exhibit luminescence as well as show a change of this property based on temperature and pH-value. This is supposed to allow for an optical detection of temperature and its alteration as well as for a detection of the pH-values of a system and a respective variation as singular as well as simultaneous analyses. In order to achieve this goal, hybrid materials have been selected according to the expertise of the two research groups that exhibit broad luminescence properties: inorganic-organic nanoparticle (AOH-NP) in the group Feldmann and metal-organic frameworks (MOFs) and coordination polymers (CPs) in the group Müller-Buschbaum. Selected compounds will be synthesized in the respective groups, investigated for the described detection options and characterized accordingly. Single compounds can undergo a change in their luminescence for a specific region of temperature and pH value. Fluorescence based detection results from distinct processes such as thermal quenching or e.g., protonation/deprotonation, and can either result in a significant alteration of intensity (“turn-off/turn-on”) or of the chromaticity of the luminescence enabling an “in-situ” detection. Furthermore, suitable candidates from both fields will be combined to even more complex hybrid materials in order to synergistically utilize two or more single effects. This shall lead to a broad range of temperature and pH being detectable. Altogether, the suitable combination of compounds and materials from both groups will be used to achieve a fluorescence thermometer as well as luminescent pH paper.