Hypersensitivity to cold exposure and emotional stimuli in hand-arm vibration syndrome patients

手臂振动综合征患者对寒冷暴露和情绪刺激的超敏反应

• 批准号: 09670392
• 负责人: HARADA Noriaki
• 金额: $ 1.86万
• 依托单位: Yamaguchi University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 1998
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09670392/
• 关键词: hand-arm vibration syndrome; cold exposure; emotional stimuli; autonomic nervous system; adrenal medulla; catecholamine; PF4; betaTG; 手腕系振動症候群; 心拍変動

Influences of season and food intake on the cold exposure test of one hand for the hand-arm vibration syndrome were investigated. Finger skin temperature in summer was higher than that in winter. Especially in winter, the finger skin temperature after food intake was higher than that in fasting condition. Heart rate variation during the cold immersion after food intake was larger than that in fasting condition.When comparing to immersing a hand in cold water at 15ﾟC for 3 minutes, method using cold water at 10ﾟC for 10 minutes indicated larger differences of finger skin temperature between hand-arm vibration syndrome patients and healthy controls with statistical significance.Evaluations of heart rate variation and catecholamines, PF4, and beta TG indicated that hand-arm syndrome patients had larger responsibility of the sympathetic nervous system and the adrenal medulla to emotional stimuli as well as cold exposure.

本文探讨了季节和食物摄入量对手臂振动综合征单手冷暴露试验的影响。夏季手指皮肤温度高于冬季。尤其在冬季，进食后手指皮肤温度高于空腹状态。进食后冷浸时的心率变异性大于空腹时的心率变异性。与15 ℃冷水浸泡3 min相比，10 ℃冷水浸泡10 min的方法显示手臂振动综合征患者与健康对照者手指皮肤温度的差异更大，具有统计学意义。β-TG和β-TG的变化表明，手综合征患者的交感神经系统和肾上腺髓质对情绪刺激和冷暴露具有更大的反应性。

项目成果

岩本美江子: "騒音等の心理的ストレス負荷による自律神経系と内分泌系の反応" 日本音響学会騒音・振動研究会. N-98-55. 1-6 (1998)

Mieko Iwamoto：“由于噪音等心理压力负荷导致的自主神经系统和内分泌系统的反应”日本声学学会噪声和振动研究小组 N-98-55 (1998)。

岩本美江子: "振動障害患者における心理的ストレッサーの尿中カテコールアミンとコルチゾール排泄量に及ぼす影響" 臨床環境医学. 7(印刷中). (1998)

Mieko Iwamoto：“心理压力因素对振动障碍患者尿儿茶酚胺和皮质醇排泄的影响”《临床环境医学》7（出版中）。

Harada N: "Hand-arm Vibration Syndrome and Medical Treatment Effects" Proceed 15th Asian Conf Occup Hlth(in press), (1997)

原田 N：“手臂振动综合症和医疗效果”，第 15 届亚洲会议 Occup Hlth（正在印刷中），（1997 年）

Laskar M S: "Effects of acute psychological stress on autonomic nervous system in hand-arm vibration syndrome patients" Proceed 8th Int Con Hand-Arm Vibration. (in press). (1999)

Laskar MS：“急性心理压力对手臂振动综合征患者自主神经系统的影响”继续第八届国际手臂振动大会。

Laskar M S: "Influence of breathing pattern on heart rate spectral power in supine position and consistency in two different divisions of the total frequency area in heart rate spectral analysis" Bull Yamaguchi Med Sch. 44. 21-26 (1997)

Laskar MS：“呼吸模式对仰卧位心率频谱功率的影响以及心率频谱分析中总频率区域的两个不同部分的一致性”Bull Yamaguchi Med Sch。