Twenty-year follow-up study of juvenile hypertensive subjects in Kyushu University

对496名20 ~ 29岁男性大学生进行了问卷调查，收缩压（S）> 140 mmHg，舒张压（D）> 90 mmHg 1978年至1990年在九州大学进行的连续3天的定期健康检查和进一步详细检查。约1，000名学生（SBP 110-124，DBP 60-74 mmHg），其身高，体重，年龄，性别和检查时间尽可能匹配，也作为血压正常（NT）的学生进行了调查。结果：（1）高血压学生180人（52%），正常对照学生216人（28%），高血压学生180人（52%），正常对照学生216人（28%）。(2)高血压学生中有51%持续高血压，而NT学生中有13%成为高血压。(3)在调查结束时，HT的发病率显着高于那些谁有一个积极的HT家族史的受试者比那些谁有一个阴性。(4)体重增加（+15%）是最大的HT受试者谁曾经是NT学生。(5)曾为NT学生的HT受试者吸烟和饮酒习惯的发生率最高。这些结果证实生活方式是维持血压正常的最重要因素之一。

We investigated by means of a questionnaire a follow-up study of 496 hypertensive (HT) male students, aged from 20 to 29 years, whose Wood pressure (BP) had been higher than 140 mmHg in systolic (S) and/or 90 mmHg in diastolic (D) at both the regular health check and further detailed examinations for 3 consecutive days carried out from 1978 till 1990 at Kyushu University. Approximately 1,000 students (110-124 in SBP and 60-74 mmHg in DBP), whose height, weight, age, sex and examination period were matched as much as possible, were also investigated as a normotensive (NT) students. We asked all subjects to measure their height, weight and sitting BP, and to tell us about their family history of HT, lifestyle such as drinking and smoking habits, physical activities and so on. The results are as follows : (1) One hundred and eighty (52 %) of HT and 216 (28 %) of NT students answered the questionnaire. (2) Hypertension lasted in 51 % out of HT students, whereas 13 % of NT students became HT.(3) The incidence of HT at the end of the investigation was significantly higher in the subjects who had a positive family history of HT than in those who had a negative. (4) The weight gain (+15%) was the greatest in HT subjects who used to be NT students. (5) HT subjects who used to be NT students showed the highest incidence of smoking and drinking habits. These results confirmed that lifestyle is one of the most important factors for keeping BP norma] throughout their life.