Twenty-year follow-up study of juvenile hypertensive subjects in Kyushu University

采用问卷调查的方法，对1978年至1990年在九州大学连续3天定期体检和进一步详细检查的496名20~29岁高血压(HT)男学生进行了追踪研究。对身高、体重、年龄、性别和考试时间尽可能匹配的约1000名学生(SBP 110-124，DBP 60-74 mm Hg)作为正常血压(NT)学生进行调查。我们要求所有受试者测量他们的身高、体重和坐位血压，并告诉我们他们的高血压家族史，生活方式，如饮酒和吸烟习惯，体育活动等。研究结果如下：(1)180名高中生(52%)和216名高中生(28%)进行了问卷调查。(2)高血压家族史阳性者高血压发生率显著高于家族史阴性者(P<0.05)。(4)曾为NT学生的超重受试者体重增加幅度最大(+15%)。(5)吸烟率和饮酒率均以曾为NT学生的HT患者最高。这些结果证实，生活方式是让他们终生保持血压正常的最重要因素之一。

We investigated by means of a questionnaire a follow-up study of 496 hypertensive (HT) male students, aged from 20 to 29 years, whose Wood pressure (BP) had been higher than 140 mmHg in systolic (S) and/or 90 mmHg in diastolic (D) at both the regular health check and further detailed examinations for 3 consecutive days carried out from 1978 till 1990 at Kyushu University. Approximately 1,000 students (110-124 in SBP and 60-74 mmHg in DBP), whose height, weight, age, sex and examination period were matched as much as possible, were also investigated as a normotensive (NT) students. We asked all subjects to measure their height, weight and sitting BP, and to tell us about their family history of HT, lifestyle such as drinking and smoking habits, physical activities and so on. The results are as follows : (1) One hundred and eighty (52 %) of HT and 216 (28 %) of NT students answered the questionnaire. (2) Hypertension lasted in 51 % out of HT students, whereas 13 % of NT students became HT.(3) The incidence of HT at the end of the investigation was significantly higher in the subjects who had a positive family history of HT than in those who had a negative. (4) The weight gain (+15%) was the greatest in HT subjects who used to be NT students. (5) HT subjects who used to be NT students showed the highest incidence of smoking and drinking habits. These results confirmed that lifestyle is one of the most important factors for keeping BP norma] throughout their life.