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Application of double scattering method using a dual-ring to formation of irradiation field for proton cancer therapy

Application of double scattering method using a dual-ring to formation of irradiation field for proton cancer therapy
双环双散射法在质子癌治疗照射场形成中的应用
批准号:
09670915
负责人:
TAKADA Yoshihisa
金额:
$1.54万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
1997
资助国家:
日本
项目状态:
已结题
起止时间:
1997 至 1998

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中文摘要
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英文摘要
A method of applying the efficient double scattering method using a dual-ring 2nd scatterer to proton cancer therapy has been clarified. Since insertion of beam modifying devices such as a range shifter and a range modulator (a bar ridge filter) modifies the lateral dose distribution, it is impossible to cover the whole depth range used for cancer treatment by a single scatterer combination. It is shown that we can obtain the uniform lateral dose distribution for the whole depth region if the covered depth of irradiation is divided into eight ranges and for each range, the appropriate combination of the first and the second scatterers are used.The method of applying the method to beam with relatively large emittance has been clarified. The six parameters specifying the lateral dose distribution are approximately optimized by changing three free parameters so that those six parameters are near to those which are optimum solution of the zero-emittance case. It is also shown that the dose distribution is rather sensitive to the selection of beam phase space parameters even if the emittance is the same. Namely focused, or diverging, or converging beams will produce different dose distributions.Since the method is sensitive to the beam misalignment, it is necessary to monitor the flatness of the distribution. For that purpose, we manufactured an ionization chamber with four identical collection electrodes placed at four quadrants of a single plane, each of them was electrically isolated from others. We tested the monitor chamber for the pulsed proton beam (5Onsec FWHM) and found that it can be used to monitor the inhomogeneity of less than 1 %.By the research, we clarified that this method can be used for proton cancer therapy effectively.
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会议论文
高田義久: "重荷電粒子線の照射野形成法,照射装置,照射の実際" 放射線物理. (出版予定).
高田义久:《重带电粒子束的辐照场形成方法、辐照设备和辐照实践》《辐射物理学》(待出版)。
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作者: []
通讯作者:
Y.Takada: ""Review of beam delivery system for radiotherapy using heavy-charged-particle beam"" Japanese Journal of Medical Physics. (to be published.).
Y.Takada:“使用重带电粒子束进行放射治疗的光束传输系统的综述”,《日本医学物理学杂志》。
DOI: --
发表时间:
期刊:
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作者: []
通讯作者:
Research and development for accurate calculation method of monitor unit for proton therapy
  • 批准号:
    22611004
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.91万
  • 财政年份:
    2010
  • 负责人:
    TAKADA Yoshihisa
  • 依托单位:
Optimization study on range-compensating bolus in proton therapy
  • 批准号:
    19591452
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.83万
  • 财政年份:
    2007
  • 负责人:
    TAKADA Yoshihisa
  • 依托单位:
Research for high-accuracy dose calculation methods for proton treatment planning
  • 批准号:
    12670851
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.18万
  • 财政年份:
    2000
  • 负责人:
    TAKADA Yoshihisa
  • 依托单位:
海外基金