Relationship between oral miniature area pH and its microbial flora.

口腔微小区域的pH漂移与其病理状态密切相关。牙菌斑-牙釉质界面、牙周袋内侧、修复体边缘附近的牙龈沟和牙间间隙是研究对象的微型区域，本研究的目的是阐明微型区域pH值与其微生物区系的关系，用Hosino方法比较牙菌斑在釉质表面和氢离子敏场效应晶体管电极(ISFET)上的细菌组成。他发现，ISFET上的菌斑成分与牙釉质上的相同。Hosino，Yamada和Nisimaki测量了各种糖产生的pH值的下降，并提出了ISFET方法用于检测食品的产酸性。Takesu用留置ISFET发现氟化物的产酸受到抑制。ONSE发现，蔗糖在离子水门汀上形成的菌斑中产生的pH比在牙釉质上形成的菌斑中的pH下降幅度小。片山研究认为，斑块的成熟度与产酸性密切相关。木村测量了牙龈沟的pH值以及由食物和饮料引起的pH值波动。Endo、Maita和Horiuchi对牙周袋的微生物区系进行了研究。牙周袋的pH值为弱酸性。牙周袋内的主要菌群由对类杆菌和微丝-唾液菌有亲和力的空间组成。此外，还对放射性遥测法测量口腔内pH进行了研究。

The pH shift of oral miniature areas is closely related to their pathological condition. The plaque-enamel interface, the inside of periodontal pockets, the gingival sulcus near the margin of restorations and interdental spaces are the miniature areas interested.The purpose of this research is to elucidate the relationship between the miniature area pH and its microbial flora.The bacterial composition of human dental plaque formed on enamel and on hydrogen-ion sensitive field effect transistor electrode(ISFET) were compared by Hosino. He found that the composition of plaque on the ISFET was the same as that on enamel. Hosino, Yamada, and Nisimaki measured the decrease of pH produced by various kinds of sugar and proposed that the ISFET method was useful to examine the acidogenicity of foods. Suppression of acid production by fluoride was found by Takaesu using indwelling ISFET. Onose found that decrease of pH produced by sucrose in plaque formed on the ionomer cement was smaller than that on the enamel. Katayama investigated that the maturity of plaque closely related to the acidogenicity. Kimura measured the pH of gingival sulcus and the pH fluctuation that was caused by food and drinks. Microbial flora of periodontal pockets was investigated by Endo, Maita and Horiuchi. The pH of periodontal pockets was weak acidic. Major flora in the periodontal pocket consisted of spaces that had affinity for bacteroides medium and mitis-salivalius medium. Radiotelemetry of intraoral pH measurement was also investigated.