Correlation between surface force and morphology of self-assembled monolayer

巯基金自组装膜作为一种最有潜力的生物分子载体，在表面组装方面得到了广泛的研究。在本项目中，我们将使用新合成的硫醇衍生物制备功能性单分子膜，使用表面力装置评估表面力与自组装膜表面形态之间的相关性，并优化条件以制备生物器件，如免疫传感器。

As a most potential solid support for biological molecules without denaturing their functions, gold thiol self-assembled monolayers (SAMs) have been studied extensively for surface fabrication. In this project we will prepare functional monolayers using newly synthesized thiol derivatives, evaluate correlation between surface force and surface morphology of the SAMs using the surface forces apparatus, and optimize the condition to fabricate biological devices such as immune sensors.