Seroepidemiology of ATL・AIDS-related viruses, and comparative virology and pathology.

ATL·AIDS相关病毒的血清流行病学、比较病毒学和病理学。

• 批准号: 01042004
• 负责人: HAYAMI Masanori
• 金额: $ 7.68万
• 依托单位: Kyoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for international Scientific Research
• 财政年份: 1989
• 资助国家: 日本
• 起止时间: 1989 至 无数据
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-01042004/
• 关键词: Adult T-cell leukemia; AIDS; Human immunodeficiency virus; Simian immunodeficiency virus; Human T-cell leukemia virus; HAM; TSP

In India, HTLV-1 sero-positive people were found. There are TSP patients just same as HAM seen in Japan. In Columbia, South America, there are HTLV-1 sero-positive people in a indigenous tribe in Andes. Also TSP patients were found. In Papua New Guinea, HTLV-1 seropositivity were found in nothern coastal areas and islands but not in central mountain areas. From AIDS/ARC patient in Ghana, two isolates of HIV were obtained. One was identified as HIV-1 but the other did not hybridize with HIV-1 and HIV-2, suggesting that the second one is defferent from known isolates of HIV.

在印度，发现了HTLV-1血清阳性者。也有和日本火腿一样的TSP患者。在南美洲的哥伦比亚，安第斯山脉的一个土著部落中有HTLV-1血清阳性的人。同时还发现了TSP患者。在巴布亚新几内亚，在北部沿海地区和岛屿发现了HTLV-1血清阳性，但在中部山区没有发现。从加纳的AIDS/ARC患者身上获得了两株HIV分离株。其中一株被鉴定为HIV-1，但另一株未与HIV-1和HIV-2杂交，这表明第二株与已知的HIV分离株不同。

项目成果

Akira, Hasegawa: "Sequence of a distinct HIV-2 isolated from Ghana showing significant divergence." AIDS and Human Retro Virus. 5. 593-604 (1989)

Akira, Hasekawa：“从加纳分离出的独特 HIV-2 序列显示出显着差异。”

Robert W.Cooper: "A lack of evidence of sexual transmission of a SIV agent in a semifree-ranging group of mandrills." AIDS. 3. 764 (1989)

Robert W.Cooper：“缺乏证据表明 SIV 病原体在半自由放养的山魈群中发生性传播。”

Meiko, Kawamura: "HIV-2 in West Africa in 1966." Lancet. i. 385 (1989)

Meiko, Kawamura：“1966 年西非的 HIV-2。”

Meiko, Kawamura: "Immunological reactivities of Ghanaian sera with HIV-1, HIV-2 and SIV_<agm>" AIDS. 3. 609-611 (1989)

Meiko, Kawamura：“加纳血清与 HIV-1、HIV-2 和 SIV_<agm>”艾滋病的免疫反应。

Hajime, Tsujimoto: "Sequence of a novel simian immunodeficiency virus from a wild-caught mandrill in Africa." Nature. 341. 539-541 (1989)

Hajime, Tsujimoto：“来自非洲野生捕获的山魈的新型猿猴免疫缺陷病毒的序列。”