Developments and Applications of Systems for Sonochemical Reactions

声化学反应系统的开发与应用

• 批准号: 01840021
• 负责人: ANDO Takashi
• 金额: $ 2.18万
• 依托单位: Shiga University of Medical Science
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Developmental Scientific Research (B).
• 财政年份: 1989
• 资助国家: 日本
• 起止时间: 1989 至 1990
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-01840021/
• 关键词: Ultrasoudn; Sonochemistry; Heterogeneous reaction; Organic synthesis; Block copolymerization

1. Developments of effective and easy use reaction systems by using a commercially available ultrasonic homogenizer were examined. The designing of the system must be considered specificities of ultrasonic wave, especially the relation of wave length and the height of solution.2. Studies of sonochemical reactions listed below were undertaken by using the developed and/or the other ultrasonic probes.(1) We found that the main reaction paths of the reduction of alkyl halide with metal hydride and the oxidation of olefin with lead tetraacetate were switched from the ionic path to the radical one by the irradiation of ultrasound.(2) Mechanochemical block copolymerization of poly (vinyl chloride) with methyl methacrylate by ultrasonic irradiation was studied. It gave fundamental informations for the development of new polymers.(3) Mechanochemical polymerization in mixtures of diallyl terephthalate and distilled water by ultrasonic irradiation was studied and the reaction mechanism was discussed.(4) The combination of hydrogen fluoride salts and aluminium fluoride was found to give efficient solid reagents for the preparation of fluorohydrines form epoxide and the halofluorination of alkenes.3. The system for a sonochemical reaction in a large scale was proposed. It was a flow system with a small reaction vessel.

1.研究了利用商业化的超声均质机开发高效、易用的反应体系。系统的设计必须考虑超声波的特殊性，特别是波长与溶液高度的关系。利用所研制的超声波探头和/或其他超声波探头进行了以下声化学反应的研究：(1)在超声波的作用下，金属氢化物还原卤代烷和四醋酸铅氧化烯烃的主要反应路径从离子路径切换到自由基路径。(2)研究了超声波辐射下聚氯乙烯与甲基丙烯酸甲酯的机械力化学嵌段共聚。研究了超声波辐射下对苯二甲酸二烯丙酯与蒸馏水的机械力化学聚合反应，并对反应机理进行了探讨。(4)氟化氢盐与氟化铝的结合为环氧化制氟化氢和卤代氟化反应提供了有效的固体剂。提出了一种大规模声化学反应系统。这是一个带有一个小反应容器的流动系统。

项目成果

Hideki Fujiwara: "Mechanochemical block copolymerization of poly(vinyl chloride)with methyl methacrylate by ultrasonic irradiation" Polymer Bulletin. 23. 27-33 (1990)

Hideki Fujiwara：“通过超声波照射进行聚氯乙烯与甲基丙烯酸甲酯的机械化学嵌段共聚”聚合物通报。

安藤 喬志: "有機合成に使える超音波装置" ファルマシア. 27. 32-34 (1991)

Takashi Ando：“用于有机合成的超声波装置”Pharmacia 27. 32-34 (1991)。

Takashi Ando and Takahide Kimura: "Ultrasonic irradiation Apparatus for Organic Synthesis" Farumasia (Pharmacia). 27. 32-34 (1991)

Takashi Ando 和 Takahide Kimura：“有机合成超声波照射装置”Farumasia (Pharmacia)。

Hideki Fujiwara and Kunio Goto: "Mechanochemical block copolymerization of poly (vinyl chloride) with methyl methacrylate by ultrasonic irradiation" Polymer Bulletin. 23. 27-33 (1990)

Hideki Fujiwara 和 Kunio Goto：“通过超声波照射进行聚氯乙烯与甲基丙烯酸甲酯的机械化学嵌段共聚”聚合物通报。

Junko Ichihara: "The Combination of Hydrogen Fluoride Salt and Aluminium Fluoride:An Efficient Solid Reagent for Epoxide Opening to Give Fluorohydorines" J.Chem.Soc.,Chem.Commun.1848-1850 (1989)

Junko Ichihara：“氟化氢盐和氟化铝的组合：环氧化物开环生成氟代氢的有效固体试剂”J.Chem.Soc.，Chem.Commun.1848-1850 (1989)