Comparison of contributions of thermosensitive tissues in central nervous system on heat loss responses in rabbits
家兔中枢神经系统热敏组织对热损失反应贡献的比较
基本信息
- 批准号:63570082
- 负责人:
- 金额:$ 1.34万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for General Scientific Research (C)
- 财政年份:1988
- 资助国家:日本
- 起止时间:1988 至 1989
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The preoptic area and anterior hypothalamus(PO/AH), medullary reticural formation(MRF) and spinal cord as thermosensitive tissues in the central nervous system were locally heated with an argon laser in order to induce heat loss responses in rabbits. Increases in ear skin temperature and respiratory rate and decrease in rectal temperature evoked by local heating were compared among the tissues.1. PO/AH and MRF Heating :(1)The Ar laser irradiation guided with a glass fiber is very useful to heat a small area in deep body tissue. (2)PO/AH and MRF were locally heated with Ar laser under no influence of thermal conduction though the thermal signals were transmitted by neurons. (3) The minimal Ar laser powers to induce the heat loss responses were 14.5 mW for PO/AH and 19.0 mW for MRF and it was significant difference,and thermal distributions of increase in brain temperature by Ar laser irradiations at these powers were calculated. (4)The ratio of PO/AH to MRF in products of heated volume and increase in temperature of over 0.50 ゚C was 1:2.94.2. Spinal Heating : (1)The argon laser guided with a glass fiber(0.4 mm in diameter) irradiated inside a guide tube(0.8 mm in diameter) which was implanted into the peridural space from lumbar vertebrae (L4/L5) to thoracic vertebrae(Th1). (2)The length of spinal cord increased more than 0.5 ゚C and maximal increase in temperature of spinal cord depended on the irradiation power as follows: 7.3 mm and 1.32 ゚C for 40 mW, 10.5 mm and 2.02゚C for 60 mW, 13.1 mm and 2.73゚C for 80 mW. (3) At all locations from Th1 to L4, the heat loss responses were evoked. (4) The heat loss responses induced by the lumbar spinal heating were no significant difference compared with that by the thoracic spinal heating.
用氩激光局部加热家兔视前区、下丘脑前部(PO/AH)、延髓网状结构(MRF)和脊髓等温度敏感组织,诱发热损失反应。比较局部加热引起的耳皮肤温度和呼吸频率的升高以及直肠温度的降低. PO/AH和MRF加热:(1)用玻璃纤维引导的Ar激光照射对于加热深部组织中的小区域非常有用。(2)PO/AH和MRF在不受热传导影响的情况下用Ar激光局部加热,尽管热信号是由神经元传递的。(3)产生热损失反应的最小Ar激光功率PO/AH为14.5mW,MRF为19.0mW,两者有显著性差异,并计算了这两种功率下Ar激光引起脑温升高的热分布。(4)体积升温大于0.50 ℃的产物中PO/AH与MRF之比为1:2.94。脊柱加热:(1)在从腰椎(L4/L5)到胸椎(Th 1)的硬膜外间隙植入的导管(直径0.8mm)内照射由玻璃纤维(直径0.4mm)引导的氩激光。(2)脊髓长度增加0.5 ℃以上,脊髓温度最大增加值与照射功率有关:40 mW为7.3mm和1.32 ℃,60 mW为10.5mm和2.02 ℃,80 mW为13.1mm和2.73 ℃。(3)在从Th 1到L4的所有位置,诱发热损失反应。(4)腰椎加热引起的热损失反应与胸椎加热相比无显著差异。
项目成果
期刊论文数量(28)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Ohwatari, N. et al.: "Effect of general anesthesia on heat loss responses during hyperthermic treatment" Hyperthermia Oncology, 321-323, 1989.
Ohwatari, N. 等人:“全身麻醉对热疗治疗期间热损失反应的影响”Hyperthermia Oncology,321-323,1989。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
Yang,G.J.et al.: "Poor heat loss ability of Pika(Wistle rabbit)" Trop.Med.30(1). 45-48 (1988)
Yang,G.J.等:“鼠兔散热能力较差”Trop.Med.30(1)。
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- 影响因子:0
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Kosaka,M;et al.: "Cerebral blood flow change due to thermal acclimation" Thermal Physiology. 463-468 (1989)
Kosaka,M;等人:“热适应导致的脑血流变化”热生理学。
- DOI:
- 发表时间:
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- 影响因子:0
- 作者:
- 通讯作者:
Ohwatari,N.et al.: "Heat loss response induced by local heating of spinal cord with Argon Laser" Trop.Med.31(3). 147-150 (1989)
Ohwatari,N.et al.:“用氩激光局部加热脊髓引起的热损失反应”Trop.Med.31(3)。
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- 发表时间:
- 期刊:
- 影响因子:0
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Nobu Ohwatari: Proceedings of 5th International Symposium on Hyperthermic Oncology.Volume I. (1989)
Nobu Ohwatari:第五届国际热肿瘤学研讨会论文集。第一卷(1989 年)
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- 影响因子:0
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OHWATARI Nobu其他文献
OHWATARI Nobu的其他文献
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{{ truncateString('OHWATARI Nobu', 18)}}的其他基金
Health information about relative measures between prevention of heatstroke in global warming and defense to Ultraviolet rays
全球变暖带来的中暑预防和紫外线防御相关措施的健康信息
- 批准号:
23650419 - 财政年份:2011
- 资助金额:
$ 1.34万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
Deterioration action by solar ultraviolet rays exposure on infection and symptom of Schistosomiasis and in symptom, and evaluation it
太阳紫外线照射对血吸虫病感染及症状的恶化作用及其评价
- 批准号:
13680630 - 财政年份:2001
- 资助金额:
$ 1.34万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Ultraviolet permeability through skin of wild animals and skin degeneration by ultraviolet rays
野生动物皮肤的紫外线透过性及紫外线引起的皮肤变性
- 批准号:
11670073 - 财政年份:1999
- 资助金额:
$ 1.34万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
ANALYSIS OF TEMPERATURE CHARACTERISTIC OF SYSTOLE IN HIBERNATOR WITH ULTRASONIC TOMOGRAPHY
超声断层扫描分析冬眠器心搏温度特性
- 批准号:
07670086 - 财政年份:1995
- 资助金额:
$ 1.34万 - 项目类别:
Grant-in-Aid for Scientific Research (C)