A Study on the Propriety of International TNM Classification of Maxillary Sinus Carcinoma

上颌窦癌国际TNM分类的适用性研究

• 批准号: 63570809
• 负责人: SAKAI Shun-ichi
• 金额: $ 0.9万
• 依托单位: Kagawa Medical School
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1988
• 资助国家: 日本
• 起止时间: 1988 至 1990
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-63570809/
• 关键词: Maxillary sinus carcinoma; International Classification; TNM classification; Combined therapy; Extensive Denker's operation; End results

Union International Center le Cancer (UICC) reached in 1987 an agreement on the TNM classification of maxillary sinus carcinoma. The TNM classification attests to its propriety by a characteristic satisfactory reproducibility, well-balanced distribution of cases, contribution to the establishment o f treatment programs, and facilitated prediction of the clinical outcome.The subjects consisted of 845 patients with maxillary sinus carcinoma treated between 1957 and 1983 whose clinical records are registrated and statistically analyzed by a personal computer.The results of the classification of 845 cases were as followed : T1 13, T2 240, T3 305, T4 287, Stage I 13, Stage II 204, Stage III 391 and Stage IV 237, respectively. The 5-year cumulative survival rates according to the clinical stage were Stage I 69%, Stage II 43%, Stage III 33% and Stage IV 14%, respectively.In addition, it was clarified that the extensive Denker's operation plays an important role to increase the success rate of the initial treatment, decrease the rate of maxillectomy and increase the survival rate, which were closely related with the local extent by T classification. These results sh owed the propriety of the International TNM Classification of maxillary sinus carcinoma.

1987年，国际癌症联合中心（UICC）就上颌窦癌的TNM分期达成一致。TNM分类以其特征性的令人满意的可重复性、病例的良好平衡分布、对治疗方案的建立的贡献，本文对1957 ~ 1983年收治的上颌窦癌845例进行了临床资料的统计分析，结果表明，上颌窦癌的临床表现与上颌窦癌的病理类型有关，而上颌窦癌的病理类型与上颌窦癌的病理类型有关，而上颌窦癌的病理类型与上颌窦癌的病理类型有关。其中T1期13例，T2期240例，T3期305例，T4期287例，I期13例，II期204例，III期391例，IV期237例。按临床分期5年累计生存率分别为Ⅰ期69%、Ⅱ期43%、Ⅲ期33%、Ⅳ期14%，并阐明扩大Denker手术对提高初治成功率、降低上颌骨切除率、提高生存率具有重要作用。T分类与局部范围密切相关。这些结果表明上颌窦癌国际TNM分类的正确性。

项目成果

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M.Miyaguchi：“鼻腔和鼻旁窦恶性肿瘤患者的多种原发性恶性肿瘤。”

S.Sakai: "Combined Therapy for maxillary sinus carcinoma with special reference to extensive Denker´s operation." Auris・Nasus・Larynx(tokyo). (1991)

S.Sakai：“上颌窦癌的联合治疗，特别是广泛的 Denker 手术”（东京）。

S.Sakai: "Astudy of The Late, Effects of Radiotherapy and Operation on Patients with Maxillary Cancer.(Asurver More Than 10Years After IniTialTreatment)" Cancer. 62. 2114-2117 (1988)

S.Sakai：“放射治疗和手术对上颌癌患者的晚期影响的研究。（初始治疗后 10 多年的 Asurver）”癌症。

酒井 俊一: "上顎洞癌併用治療における拡大デンケル手術の役割" 日本耳鼻咽喉科学会会報. 94. 214-224 (1991)

Shunichi Sakai：“扩大 Denkel 手术在上颌窦癌联合治疗中的作用”日本耳鼻喉科学会通报 94. 214-224 (1991)。

S. Sakai: "The role of extensive Denker's operation in combined therapy for maxillary sinus carcinoma" J. Otolaryngol. Jpn.,. 94(2). 214-224

S. Sakai：“广泛的 Denker 手术在上颌窦癌联合治疗中的作用”J. Otolaryngol。