MR (Magnetic Resonance) Evaluation of Bone Marrow Dynamics in Hematological Disorders

1 .正常骨髓MRI(1)最佳脉冲序列；对活体骨髓动力学成像的最佳脉冲序列为双回波STIR；TR;2000秒，TI 160msec。和TE 20毫秒。用于短时间和120毫秒的搅拌。longTE。(2)骨髓MRI正常；，短TE的STIR显示正常中矢状腰椎椎体周围高信号，中央低信号。高信号对应红骨髓，低信号对应黄骨髓。脂肪变性发生于下腰椎和头侧上升方向。不同血液学疾病的MRI分别用STIR和long两种TE进行扫描。再生障碍性贫血表现为全低信号，80%为短TE。多发性骨髓瘤、慢性骨髓性白血病、骨髓增生异常综合征和骨髓纤维化在伴短TE的STIR表现为均匀或非均匀的高信号，而在伴长TE的STIR表现为信号衰减。短TE的STIR突出水成分，长TE的STIR增强水成分。

l. Normal Bone Marrow MRI(1) Optimal Pulse Sequences ; The optimal pulse sequences to image in vivo bone marrow dynamics were STIR with double echo ; TR ; 2000sec, TI 160msec. and TE 20msec. for STIR with shortTE and 120 msec. for longTE.(2) Normal Bone Marrow MRI ; , STIR with short TE disclosed normal mid-sagittal lumbar vertbrae to be high signal in the peripheral portion of the vertbrae and low signal in the center. The high signal corresponds to red marrow and low signal to yellow marrow. The fatty degeneration took place from lower lumbar vertbra and-ascended cephalad direction.2. Abnormal Bone Marrow MRIEighty-four MRI in various hematological disorders were obtained with STIR with short and long TE. Aplastic anemia showed completely low signal with STIR with short TE in 80%. Multiple myeloma, Chronic myelogenous leukemia, Myelodysplastic syndrome and Myelofibrosis revealed either homogeneous or hetrogeneous high signals with STIR with short TE, while their signals decayed with STIR with long TE in Cronic myelogenous leukemia. STIR with short TE highlights water component and STIR with long TE enhances water T2 component.