A Basic Study of Sealed Joint with Artificial Synovial Fluid

人工滑液封闭关节的基础研究

• 批准号: 01570835
• 负责人: IKEUCHI Ken
• 金额: $ 1.34万
• 依托单位: Kyoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1989
• 资助国家: 日本
• 起止时间: 1989 至 1990
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-01570835/
• 关键词: Sealed joint; Artificial joint capsule; Synthetic sinovial fluid; Total hip prosthesis; 生体反応; 人工関節液; 人工股関節; 人工関節; 潤滑; 摩擦係数

Basic characteristics of a novel sealed type artificial joint was investigated. The results show that the wear rate of HDPE socket may be drastically reduced due to the lubrication effect of synthetic synovial fluid. Since the artificial joint capsule trapps the wear particles, biological reaction against HDPE particles is completely protected. The purpose of this study was to investigate the possible design of a sealed joint for long term use. The results of this reserach project is as follows ;(1) Two types of artificial joint capsule of silicon rubber or polyurethane were produced by casting. The sealing performamce of these capsules were tested for several kinds of liquid.(2) The range of flexion-extension angle of the sealed joint exceeded 80degrees, and that of external-internal rotation exceeded 40degrees. Joint capsule of both materials showed sufficient deformability not to limit the joint movement, while the joint capsule of silicon rubber showed better deform ability.(3) For large deformation, the resisting moment showed non-linear characteristics. At the same time, buckling phenomenon was observed with wrinkles on its surface.(4) Since large moment was measured near the center of the joint capsule, it is necessary to thicken this place.(5) Wear test was performed with several liquids containing castor oil with a pin-on disk apparatus. The friction coefficient was reduced to be 0.02 with castor oil, and wear rate with castor oil was less than 1/10 of that with bovine serum.

研究了一种新型密封式人工关节的基本特性。结果表明，由于合成滑液的润滑作用，HDPE承窝的磨损率可显著降低。由于人工关节囊捕获磨损颗粒，因此完全保护了对HDPE颗粒的生物反应。本研究的目的是调查长期使用的密封接头的可能设计。本课题的研究结果如下：（1）采用铸造法制备了硅橡胶和聚氨酯两种人工关节囊。对几种液体进行了密封性能试验。(2)密封关节的屈伸角度范围超过80 °，外旋角度范围超过40 °。两种材料的关节囊均表现出足够的变形能力，不限制关节活动，而硅橡胶的关节囊表现出更好的变形能力。(3)大变形时，抗力矩呈现非线性特征。同时，观察到屈曲现象，在其表面上的皱纹。(4)由于在关节囊中心附近测得了较大的力矩，因此有必要对该位置进行测量。(5)用销盘式磨损试验机对几种含蓖麻油的液体进行了磨损试验。蓖麻油的加入使摩擦系数降低到0.02，磨损率小于牛血清的1/10。

项目成果

K.IKEUCHI and M.OKA: "Elastoーmixed lulrication in total hir prostheses" Frontiers of Medical and Biological Engineering. 2. 167-170 (1990)

K.IKEUCHI 和 M.OKA：“全假体中的弹性混合润滑”《医学和生物工程前沿》2. 167-170 (1990)。

K. Ikeuchi and M. Oka: "Elasto-Mixed Lubrication in Total Hip Prostheses" Frontiers of Medical and Biological Engineering. 2-3. 167-170 (1990)

K. Ikeuchi 和 M. Oka：“全髋关节假体中的弹性混合润滑”医学和生物工程前沿。

K. Ikeuchi and M. Oka: "A Sealed Hip Prostheses with Synthetic Synovial Fluid" Proc. 1990 Annual Meeting JSOB. 12. (1991)

K. Ikeuchi 和 M. Oka：“带有合成滑液的密封髋关节假体”Proc。

池内 健: "密封式人工関節の開発" 病態生理. 9. 733-737 (1990)

Ken Ikeuchi：“密封人工关节的发展”病理生理学 9. 733-737 (1990)。

池内 健・岡 正典: "人工関節液を用いる密封式人工股関節" 整形外科バイオメカニクス. 12. (1991)

Ken Ikeuchi 和 Masanori Oka：“使用人工关节液密封人工髋关节”骨科生物力学 12。（1991）