Investigation of Naturally Occurring Drug Materials in Indonesia-3

印度尼西亚是一个世界著名的自然资源丰富的国家，这可能保证我们有许多迄今为止未知的药用植物。然而，对这些药用植物生物活性原理的化学和生物学研究尚未充分开展。我们的研究项目名为“印尼天然存在的原料药调查-3”，旨在揭示印尼天然存在的原料药即药用植物，并为日本与印尼之间学术交流的发展指明方向。1990年，我们在印度尼西亚苏门答腊岛的明古鲁省、廖内省和北苏门答腊省进行了调查，从当地人那里收集了360种传统药用植物的资料，并收集了68种药用植物进行化学研究，将在大阪大学进行。1991年，所有标本在印度尼西亚茂物的Bogoriense植物标本馆进行了植物学鉴定。在大阪大学用几种色谱技术和生物测定法对这些标本的酒精提取物进行了制备和检验。分析研究正在进行中。到目前为止，我们已经获得了一些有希望的证据，因此，对我们调查中收集的这些材料的化学和生物学研究可能会引导我们发现新的生物活性物质。与印度尼西亚参与组织印度尼西亚生物研究与发展中心lipi的合作进展非常顺利。这种理想的合作今后肯定会以这种方式继续下去。

Indonesia is a world-prominent country rich in natural resources an this may guarantee us for many medicinal plants hitherto unknown to be available. However, chemical and biological investigations of bioactive principles in those medicinal plants, have not yet been fully carried out.Our research project entitled "Investigation of Naturally Occurring Drug Materials in Indonesia-3" aims at revealing the naturally occurring drug materials, i. e. medicinal plants, in Indonesia and points towards the development of the academic exchange between Japan and Indonesia.In 1990, we surveyed in Province Bengkulu, Riau, and North Sumatera in Sumatera Island, Indonesia and collected information about 360 kinds of traditionally used medicinal plants from local people and gathered 68 kinds of medicinal plants for chemical study, which will be carried out at Osaka University.In 1991, all specimens were botanically identified at Herbarium Bogoriense, Bogor, Indonesia. The alcoholic extract of these specimens were made and examined by means of several kinds of chromatographic technique and bioassay at Osaka University. The analytical studies are in progress. We have so far obtained some promising evidence so that the chemical and biological studies of those materials collected in our survey may lead us to find new biologically active substances.The collaboration with Research and Development Center for Biology-LIPI, Indonesia, which is the Indonesian participating organization, has been proceeded very smoothly. The desirable collaboration will certainly be continued in this manner hereafter.