Use of Redox theory in the perioperative metabolic support and the treatment in liver surgery and transplant.

通过与发达国家移植中心的国际合作研究，氧化还原理论已被证明在肝移植领域是有用的。在术前阶段，通过动脉酮体比值（AKBR）评估供体肝脏的存活率，AKBR值越高，供体肝脏的存活率越高。在手术阶段，通过AKBR测量手术应力，并改进手术技术以最大限度地减少应力。术后AKBR可作为早期移植物存活的指标，术后AKBR恢复不充分意味着移植物功能不全，应行再次移植。这些结果结合我科自1990年6月以来进行的活体部分肝移植手术，已成功29例。因此，氧化还原理论在肝外科和肝移植领域得到了广泛的应用，并取得了成功。

As a result of the international cooperative study with the transplantation centers in advanced countries, Redox theory has been proven to be useful in the field of liver transplantation. In the preoperative stage, estimation of donor liver viability before procurement has been performed by means of arterial ketone body ratio (AKBR), and the higher is the valve of AKBR, the more viable is the donor liver. In the operative stage, operative stress has been measured by means of AKBR, and operative techniques have been refined to minimize the stress. In the postoperative stage, AKBR can be the indicator of early graft survival and inadequate recovery of AKBR after operation means the inadequate function of the transplanted graft, and retransplant should be performed. All these results were integrated in the living related partial liver transplantations, which are performed in our department, and 29 cases have already been operated successfully since June, 1990.Thus, in both fields of hepatic surgery and liver transplantaion, Redox theory is widely applied and successful results have been made.