The effect of pulsing electro magnetic Fields on the Fracture repair

本研究旨在建立脉冲电磁场（pemf）加速骨愈合的最佳照射条件，并开发动物用便携式脉冲电磁场治疗仪。利用家兔和狗的骨折模型研究得到的最佳脉冲电磁场辐照条件为：磁场强度2高斯，脉宽25 μ m，频率10 Hz。在这种照射条件下，对3只玩具犬的骨折不愈合进行了临床试验。骨折通过手术稳定，然后在前6周和之后的12小时/天持续照射。照射8 ~ 9周后获得临床愈合。临床应用PEMFs治疗23匹赛马的新鲜骨折，并将结果与未照射的结果进行比较。与未接受放射治疗的动物相比，20匹马（87%）的早期临床愈合得到影像学证实。这些结果表明，pemf加速了动物骨愈合过程，对治疗骨不连或新骨折非常有效。最后，研制成功了便携式无线型动物用pemf装置。固定照射条件和使用简单的电路与小电池（AM3）使一个小而轻（8 × 5.5 × 1.5厘米和100克重）的装置成为可能。

This study was aimed to establish the optimal irradiation condition for pulsing electromagnetic fields(PEMFs)to accelerate the bone healing process,and to develop the portable PEMFs apparatus for animals.The optimal irradiation conditions of PEMFs obtained in the studies using the fracture models of rabbits and dogs were 2 gauss of magnetic field intensity, 25 musec of pulse width, and 10 Hz of frequency. Clinical trials of PEMFs with this irradiation condition were applied to 3 toy breed dogs with nonunion fractures. The fractures were stabilized surgically, then irradiated continuously during the first 6 weeks and for 12 hours/day thereafter. Clinical unions were obtained after 8 to 9 weeks of irradiation. PEMFs were also applied clinically for treatment of fresh fracture in 23 racing horses, and the results were compared to those without irradiation. Earlier clinical unions demonstrated radiographically were obtained in 20(87%) horses compared to non-irradiated animals. These results suggest that PEMFs accelerate bone healing process in animals and quite effective as the treatment of nonunion or fresh fractures.Finally, the portable and wireless type PEMFs apparatus for animals was successfully developed. Fixation of irradiation condition and a use of simple electric circuit with small batteries(AM3) made a small and light(8 by 5.5 by 1.5 cm and 100g weight) apparatus possible.