The effect of endurance training on exercise-induced bronchospasm.

哮喘儿童经常由于运动引起的支气管痉挛（EIB）而经历身体活动的限制。因此，有必要控制他们的EIB，以帮助他们的身体和社会成熟。在本研究中，我们试图通过在不同强度的有氧运动中测量的生理反应来阐明与EIB严重程度相关的危险因素和运动条件，从而确定哮喘儿童运动治疗的最佳强度。最后，研究耐力训练对EIB的影响。在一项为期三年的研究的第一年，我们评估了运动强度对EIB的影响，以确定运动疗法的最佳运动强度。根据我们的研究结果，发现EIB的严重程度与运动强度有关。研究还确定，125%乳酸阈值强度（125% LT）是运动强度的上限，这允许更多的哮喘儿童提高他们的有氧运动能力，并且在没有任何严重支气管痉挛的情况下进行运动。在这项研究的第二年，耐力训练在循环计力器上进行，每次30分钟，每周6次，持续4周，强度为125%。结果，耐力训练提高了他们的有氧能力，也降低了绝对工作量下EIB的严重程度。因此，EIB严重程度的降低可归因于有氧能力的增加。然后我们将培训期限延长了2个月。经过2个月的耐力训练，发现EIB的严重程度不仅降低了绝对工作量，而且降低了相对工作量。在相对工作量下，EIB严重程度的降低表明，运动训练可能会导致一些导致EIB的临床因素发生变化。在本研究的第三年，我们检测了3周去训练对6周耐力训练效果、EIB、支气管高反应性和有氧工作能力的影响。根据我们的研究结果，去训练后，EIB适应性和支气管高反应性的丧失可能比有氧工作能力的丧失要慢。因此，耐力训练似乎可以改变一些引起EIB的临床因素。因此，耐力训练不仅提高了有氧运动能力，而且降低了EIB的严重程度和支气管高反应性，因此被认为是改善临床表现的有效治疗方法。少

Asthmatic children often experience limitations of their physical activity due to exercise induced bronchospasms (EIB). It is therefore necessary to control their EIB in order to help them in their physical and social maturation. In this study we attempt to clarify the risk factors and the exercise conditions which relate to the severity of EIB, based on the physiological responses measured during various intensities of aerobic exercise and thus determined the optimal intensity of exercise therapy in asthmatic children. Finally, the influence of endurance training on the EIB was also investigated.In the first year of a three-year study, the effects of exercise intensity on EIB was evaluated in order to determine the optimal exercise intensity for exercise therapy. Based on our findings, the severity of EIB was found to depend on the exercise intensity. It was also determined that a 125% intensity of the lactate threshold (125% LT) is the upper limit of exercise intensity which allows a … More sthmatic children to improve their aerobic working capacity and perform without suffering any severe bronchospasms. In the second year of this study, endurance training was performed on a cycle ergometer for 30min, 6times a week for 4weeks at 125% LT.As a result, endurance training improved their aerobic capacity and also reduced the severity of EIB at an absolute work load. It was thus suggested that the reduction in the severity of EIB was attributable to the increase in the aerobic capacity. We then prolonged the training term for 2 months. After 2 months of endurance training, the severity of EIB was found to have reduced not only the absolute but also the relative work load. This reduction in the severity of EIB at a relative work load indicates that some changes in the clinical factors which cause EIB might occur due to exercise training. In the third year of this study, the influence of detraining for 3 weeks on the effect of endurance training for 6 weeks, EIB, bronchial hyperreactivity and aerobic working capacity was examined. Based on our findings, the loss of adaptation for EIB and bronchial hyperreactivity may be slower than that of the aerobic working capacity following detraining. Endurance training thus appears to alter some of the clinical factors which cause EIB.It was therefore concluded that endurance training not only improved the aerobic working capacity but also reduced the severity of EIB and bronchial hyperreactivity, and is thus considered to be an effective therapy for improving clinical manifestations. Less