A Study on risk factors of gastrointestinal cancer in Taivan

本研究旨在揭示台湾地区胃癌、结直肠癌的发病率、分布及相关危险因素。台湾地区胃癌死亡率下降趋势及病理类型分布与日本大致相同。死亡统计显示，过去15年来，台湾地区结肠癌死亡率持续高于直肠癌。临床数据还显示，结肠癌在肠癌患者中占主导地位。这与日本的趋势不同，日本的趋势表明结肠癌最近有所增加。然而，台湾结直肠癌的病理结果与日本人的分布几乎相同。对台湾饮食因素和既往胃癌病史的初步病例对照研究显示，高血压病史和经常摄入香料(2-3次/周或更多)显著降低了风险。台湾一项结直肠癌病例对照研究显示，每日进食咸食显著增加风险，而经常进食肉类(1-2次/周或以上)则显著降低风险。由于这些分析是在少数病例中进行的，因此有必要继续对这些可能导致胃癌和结直肠癌的危险因素进行更详细的研究。

This study was conducted to reveal the frequency and distribution on stomach cancer and colorectal cancer in Taiwan and the risk factors of these diseases among Taiwanese.As for stomach cancer in Taiwan, the decreasing trend of mortality and the distribution of pathological types were almost the same as in Japan.Mortality statistics showed that the death rate from colon cancer was constantly higher than that from rectal cancer in Taiwan during the past 15 years. Clinical data also showed the colon cancer predominance among intestinal cancer patients. These are different from Japanese trend which showed the recent increasing of colon cancer. However, the pathological findings on colorectal cancer in Taiwan showed almost the same distribution as Japanese.Preliminary case-control study on dietary factors and past medical histories stomach cancer in Taiwan showed that the history of hypertension and the frequent intake (2-3 times/week or more) of spices decreased the risk significantly. A case-control study for colorectal cancer in Taiwan showed that daily intake of salty food significantly increased the risk and the frequent intake (1-2 times/week or more) of meat significantly decreased the risk.It is necessary to continue to study more on these possible risk factors of stomach cancer and colorectal cancer in details as these analyses were conducted on a small number of cases.