Development of Artery Repairing Material using Shape Memory Alloy for Cerebral Aneurysm

形状记忆合金脑动脉瘤动脉修复材料的研制

• 批准号: 03305008
• 负责人: FUNAKUBO Hiroyasu
• 金额: $ 8.32万
• 依托单位: Shibaura Institute of Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Co-operative Research (A)
• 财政年份: 1991
• 资助国家: 日本
• 起止时间: 1991 至 1993
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-03305008/
• 关键词: neurosurgery; cerebral aneurysm; subarachoid anesthesia; catheter coil method; shape memory alloy; artery repairing material; thrombus; microcatheter; 脳動派瘤; 血管内ステント; 血管補修; カテ-テル

(1)Development of Artery Repairing Material using Shape Memory Alloy for Cerebral AneurysmThis reports studies the new technique for treatment of cerebral aneurysm. The new technique of intra-aneurysmal thrombosis via an endovascular approach has been conceived in attempt to experimentation. We will report the results for the basic characteristics of material on which it based, repairing material using TiNi shape memory alloy, repairing material apart from stainless steel delivery guidewire, a microcatheter, and shape recovery device. The shape memory alloy is soft and will adapt to the size and shape of the cerebral aneurysm. This technique consists of the production of an endovascular thrombus by a positively fixed endovascular shape memory alloy. After shape memorization process we get by DSC the curves. A newly developed microcatheter, the ring shaped electrodes are made from whitegold wire which connect the electrodes to the high frequency electrical current generator. The results … More observed in our experimental work using the repairing material. The intra-vascular navigation and the positioning of a microcatheter within the aneurysm model can be fixed performed.(2)Development of a Vessel Repairing Cover using Shape Memory AlloyThis reports studies the following repairing matrial using shape memory alloy for cerebral aneurysm. Our resarch is developing is a vessel repairing cover which use a TiNi shape memory alloy, and the shape recovery applicator. In advance of the vessel surgery, shape memory alloy wire which has been memorised to almost the diameter of the vessel is spread is tucked around the warp on a weaving machine. The vessel repairing cover is applied near the bleeding region and operated causing the heated, after the repairing cover is shape memory the vessel is wrapped up in the cover. Animal experiment is performed to evaluate the developed vessel repairing cover by using a dog of carotid arteries. The vessel repairing cover was realized and effectiveness of new approach was confirmed. Less

(1)形状记忆合金脑动脉瘤动脉修复材料的开发本报告研究治疗脑动脉瘤的新技术。通过血管内途径形成动脉瘤内血栓的新技术已经在尝试实验中构思出来。我们将报告其基础材料、使用TiNi形状记忆合金的修复材料、除不锈钢输送导丝之外的修复材料、微导管和形状恢复装置的基本特性的结果。形状记忆合金很软，可以适应脑动脉瘤的大小和形状。该技术包括通过正向固定的血管内形状记忆合金产生血管内血栓。形状记忆过程结束后，我们通过 DSC 得到曲线。一种新开发的微导管，环形电极由白金线制成，将电极连接到高频电流发生器。我们在使用修复材料的实验工作中观察到了结果。血管内导航和微导管在动脉瘤模型内的定位可以被固定进行。(2)使用形状记忆合金的血管修复罩的开发该报告研究了以下使用形状记忆合金修复脑动脉瘤的材料。我们正在研发一种使用TiNi形状记忆合金的血管修复罩，以及形状恢复涂抹器。在血管手术之前，将已记忆的形状记忆合金丝铺展到几乎与血管直径相同的位置，并将其塞入织机上的经纱周围。将血管修补罩贴在出血区域附近并进行操作使其受热，当修补罩形状记忆后，将血管包裹在罩内。使用狗的颈动脉进行动物实验以评价所开发的血管修复罩。实现了船舶修理罩，证实了新方法的有效性。较少的

项目成果

Hiroyuki Koyama: "Development of a Vessel Repairing Cover using Shape Memory Alloy" J.of Precision Machinery Incorporating Life Support Technology. 4. 268-269 (1993)

Hiroyuki Koyama：“使用形状记忆合金开发血管修复罩”J.of Precision Machinery Incorporated Life Support Technology。

園田 善之: "形状記憶合金を用いた血管補修カバーの開発" 第8回エル・エス・ティ学会大会講演予稿集. 53 (1992)

Yoshiyuki Sonoda：“使用形状记忆合金开发血管修复覆盖物”第8届LST学会会议记录53（1992）。

園田善之: "形状記憶合金を用いた血管補修カバーの開発" 第8回エル・エス・ティ学会大会講演予稿集. 53 (1992)

Yoshiyuki Sonoda：“使用形状记忆合金开发血管修复覆盖物”第8届LST学会会议记录53（1992）。

小山 浩幸: "脳動脈瘤治療のための形状記憶合金による血管補修材の開発(第2報)" 1992年度精密工学会秋季大会学術講演会論文集. 337-338 (1992)

小山弘之：“使用形状记忆合金治疗脑动脉瘤的血管修复材料的开发（第2次报告）”1992年日本精密工程学会秋季会议学术会议论文集337-338（1992）。

小山浩幸: "脳動脈瘤治療のための形状記憶合金による血管補修材の開発(第1報)" 1992年度精密工学会春季大会学術講演会論文集. 987-988 (1992)

Hiroyuki Koyama：“使用形状记忆合金治疗脑动脉瘤的血管修复材料的开发（第一次报告）”1992年精密工程学会春季会议学术会议记录987-988（1992）。