細胞エネルギ-共役系の構築と調節

细胞能量耦合系统的构建与调控

• 批准号: 03354030
• 负责人: 安楽 泰宏
• 金额: --
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Co-operative Research (B)
• 财政年份: 1991
• 资助国家: 日本
• 起止时间: 1991 至 无数据
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-03354030/
• 关键词: 重点領域研究; 細胞エネルギ-; ATP合成酵素; 呼吸酵素; 液胞型ATPase; 能動輸送蛋白

本研究班は重点領域研究「細胞エネルギ-共役系の構築と調節」(平成4年〜6年度)を発足させるために必要な計画大網、研究課題、研究組織、研究経費等の重要事項を調査審議するために設けられた。この目的を達成するため、以下に述べる諸調査・業務を行なった。1)計画研究として提案されている4課題:[1]液胞型ATPaseの細胞生理機能と分子メカニクス,[2]ATP合成酵素の高次構造と反応機構,[3]電子伝達酵素複合体の分子構築と反応機構,[4]共役物質輸送系ネットワ-クの構築と調節に対し,国の内外における研究の現状と動向,研究課題と組織などに関する基盤調査を行なった。2)これらの調査結果に基づき,研究代表者は担当幹事と常時連絡をとりつつ,本研究領域に関する全体構想および研究体制の素案をとりまとめ,稟議に付した。ついで合同班会議を開催して素案を確認し,この研究領域の新しい展開を目指した年次計画を審議するとともに,計画研究課題担当予定者に対し,研究方針と目的の了承,共同研究体制における相互協力を要請した。3)上記の諸研究業務は文部省学術国際局研究助成課および学術調査官と随時連絡をとりつつ逐行された。また,研究助成課の指示の下に,重点領域研究「細胞エネルギ-共役系の構築と調節」の研究組織および班員班友名薄を作成し,更に,当該研究にかかわる平成4年度審査会開催のための業務連絡,経理事務を代行した。

This research group will investigate and review important issues such as the necessary planning network, research topics, research organizations, and research expenses in the key field of research,"Construction and regulation of cell growth and co-operation systems"(Heisei 4 - 6). This goal is achieved through investigations and operations described below. 1)Project research proposals include four topics:[1] Cellular physiological functions and molecular mechanisms of ATPase,[2] Higher-order structure and reaction mechanism of ATP synthase,[3] Molecular architecture and reaction mechanism of electron transfer enzyme complex,[4] Construction and regulation of co-active substance transport system, research status and trends at home and abroad, research topics and organization, and substrate modulation. 2) Based on the investigation results, the research representative shall act as the director and contact with each other regularly, and all the hypotheses related to this research field and the elements of the research system shall be submitted and paid. Contract class meetings are held to facilitate the confirmation of proposals, the development of new research areas, the direction of annual plans, the consideration of project research topics, the commitment of research policies and objectives, and the request for mutual cooperation in joint research systems 3)The above research activities are carried out by the Research Assistant Division of the Academic International Bureau of the Ministry of Education and the Academic Investigator. Under the instruction of the research assistant course, the research organization and the class member list of the key field research "cell growth-construction and regulation of the common service system" were prepared, and the business liaison and management affairs were promoted when the research was started at the 4th annual review meeting.