APPLICATION OF PEN SHEET TO ARTIFICIAL SKIN AND MANUFACTURING OF CONTINUOUS PAPER-MAKING MACHINE

α-甲壳素和β-甲壳素的固体高分辨核磁共振谱可以相互区分，也可以与X-射线或红外光谱相区分。从蟹壳或虾壳中提取的甲壳素在一般有机溶剂中微溶，由于其刚性的晶体结构而具有较差的反应性。另一方面，从鱿鱼骨中提取的β-甲壳素在用水研磨时很容易形成浆料。这是导致Lolio PEN甲壳素的疏松结晶结构和高亲水性的原因。因此，用β-甲壳素制备纸页比不加粘结剂的甲壳素容易得多。用Lolio PEN凝胶直接制取片材比用蟹壳制作非织造布具有更大的经济优势。Lolio笔手工制作的甲壳素纸的耐破系数为7.4，断裂长度为6.9公里，而蟹壳甲壳素纸的耐破度和断裂长度分别为1.0和3.0公里。根据杨氏模数计算的刚性或刚性，Lolio钢笔纸明显比蟹壳钢笔纸柔软。此外，还观察到了较高的透湿性和回潮率，对纤维蛋白原、白蛋白或丙种球蛋白等血液蛋白有很强的亲和力，溶菌酶的生物降解速度很慢。因此，笔片似乎更适合于临时人造皮肤。在本报告中，研究了以机械打浆的Lolio笔甲壳质为原料直接制备甲壳素片材。甲壳素连续造纸机是在我们的机械车间进行小试设计和建造的。该机能以0.5m/min的速度制备出长30m、宽80 mm的纸张。

High resolution ^<13>C NMR spectra of alpha-chitin and beta-chitin in solid state can be distinguished from each other as well as the x-ray patterns or IR spectra. alpha-Chitin from crab or shrimp shell is known to be slightly soluble in general organic solvents and to have poor reactivity due to its rigid crystalline structure. beta-Chitin, on the other hand, from squid bone of Loligo pen, easily forms slurry when it was ground with water. This is responsible for the loose crystalline structure and the high hydrophilicity of Loligo pen chitin. Therefore it is much easier to prepare the paper sheet from beta-chitin than alpha-chitin without binder. Direct sheet preparation from Loligo pen gel is economically of greater advantage than nonwoven sheet from crab shell. The hand-made chitin paper from Loligo pen shows a high bursting factor of 7.4 and breaking length of 6.9 Km, compared with those of alpha-chitin from crab shell, 1.0 and 3.0 Km. The Loligo pen paper is obviously softer than that from crab shell as to rigidity or stiffness calculated from Young modulus. Furthermore the higher permeability of moisture together with water regain, a strong affinity for blood protein such as fibrinogen, albumin or gamma-globulin, and slow biodegradation by lysozyme were observed. Thus the pen sheet seems to be more suitable for temporarily artificial skin.In this report, the direct preparation of chitin sheet from mechanically beated loligo pen chitin was investigated. A continuous paper-making machine for the chitin was designed in bench scale and constructed in our Machine Shop. Paper of 30m long and 80mm wide can be prepared by the machine at the speed of 0.5m/min.