A cyclic ion-mobility mass spectrometer for resolving molecular isomers

用于解析分子异构体的循环离子淌度质谱仪

• 批准号: LE220100031
• 负责人: Prof Stephen Blanksby
• 金额: $ 42.07万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2022
• 资助国家: 澳大利亚
• 起止时间: 2022-06-01 至 2023-05-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE220100031
• 关键词: cyclic; ion; mobility; mass; spectrometer

Both our fundamental understanding of the natural world and our ability to shape new functional materials depends on our ability to assign molecular structure. Rapid assignment of molecular structures within complex biological or synthetic mixtures and, particularly, the differentiation between closely related structures (i.e., isomers) is a frontier challenge for chemists and biologists alike. The requested infrastructure directly addresses this challenge by making next-generation (cyclic) ion-mobility mass spectrometry available to Australian researchers for the first time. This new capability will drive biomolecular discovery across both plant and animal kingdoms, and accelerate advances in materials science.

我们对自然世界的基本理解和塑造新功能材料的能力都取决于我们分配分子结构的能力。在复杂的生物学或合成混合物中的分子结构快速分配，尤其是密切相关的结构（即异构体）之间的分化是化学家和生物学家的领域挑战。要求的基础架构通过首次为澳大利亚研究人员提供下一代（循环）离子移动性质谱法直接解决了这一挑战。这种新的能力将推动动植物界的生物分子发现，并加速材料科学的进步。