Identifying tear lipids, their deposition onto contact lenses and their role in the development of dry eye

识别泪脂、它们在隐形眼镜上的沉积及其在干眼发展中的作用

• 批准号: LP0989883
• 负责人: Prof Stephen Blanksby
• 金额: $ 21.01万
• 依托单位: University of Wollongong
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-09-30 至 2012-09-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP0989883
• 关键词: Identifying; tear; lipids; their; deposition

Lipids provide a critical layer in the human tear film that retards evaporation and helps nourish and protect the eye. We will identify the molecules within this essential "oil slick" to better understand dry eye syndrome and the discomfort associated with wearing contact lenses. This may lead to new treatments for dry eye and novel technologies that provide greater comfort for the ~120,000 Australians who wear contact lenses. This collaborative research directly supports the mission of a respected non-profit organisation (Institute for Eye Research) and will train scientists in world-leading analytical technologies that are essential to Australia's emerging biotechnology industries.

脂质在人的泪膜中提供了一个关键层，可以延缓蒸发，帮助滋养和保护眼睛。我们将识别这种基本的“浮油”中的分子，以更好地了解干眼症和与戴隐形眼镜相关的不适。这可能会导致干眼症的新治疗方法和新技术，为约12万戴隐形眼镜的澳大利亚人提供更大的舒适度。这项合作研究直接支持一个受人尊敬的非营利组织（眼科研究所）的使命，并将培训科学家掌握世界领先的分析技术，这对澳大利亚新兴的生物技术产业至关重要。