Identifying tear lipids, their deposition onto contact lenses and their role in the development of dry eye
Identifying tear lipids, their deposition onto contact lenses and their role in the development of dry eye
批准号:
LP0989883
负责人:
Prof Stephen Blanksby
金额:
$21.01万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Linkage Projects
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-09-30 至 2012-09-30
中文摘要
类脂在人类泪膜中提供了一层关键的层,延缓了蒸发,有助于滋养和保护眼睛。为了更好地了解干眼症和与戴隐形眼镜相关的不适,我们将鉴定这种必不可少的“浮油”中的分子。这可能会带来治疗干眼症的新疗法和新技术,为大约12万戴隐形眼镜的澳大利亚人提供更大的舒适性。这项合作研究直接支持一个受人尊敬的非营利性组织(眼科研究所)的使命,并将培训科学家掌握世界领先的分析技术,这些技术对澳大利亚新兴的生物技术产业至关重要。
英文摘要
Lipids provide a critical layer in the human tear film that retards evaporation and helps nourish and protect the eye. We will identify the molecules within this essential "oil slick" to better understand dry eye syndrome and the discomfort associated with wearing contact lenses. This may lead to new treatments for dry eye and novel technologies that provide greater comfort for the ~120,000 Australians who wear contact lenses. This collaborative research directly supports the mission of a respected non-profit organisation (Institute for Eye Research) and will train scientists in world-leading analytical technologies that are essential to Australia's emerging biotechnology industries.
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