Establishing a Core Unit for Research and Treatment for patients with antibody-mediated neurological diseases

Z项目旨在提供管理和结构框架，以有效协调和运行BecauseY的许多实验和临床活动。它代表了拟议中的柏林大学研究和治疗核心单位的核心特征，作为诊断和治疗抗体介导的神经系统疾病的独特综合中心。这一核心单位将与所有次级项目密切联系，促进概念交流，并提供基础设施支助。医务人员不仅将协调CRU相关患者在医院的整个路径，而且还将涵盖从早期诊断到病例的跨学科检查（例如，在神经免疫学委员会）到创新的个性化治疗的个体抗体介导的疾病。它将照顾所有形式的抗体介导的神经系统疾病的患者，如自身免疫性脑炎，抗体介导的痴呆症，神经肌肉疾病，视神经肌萎缩症，与自身抗体有关的发育障碍，神经精神类风湿性疾病，免疫介导的精神病和抗体相关的神经病。

The Z project aims for providing the administrative and structural framework to efficiently coordinate and run the many experimental and clinical activities of BecauseY. It represents the central feature of the proposed university-based Core Unit for Research and Treatment in Berlin as a unique comprehensive center for diagnosing and treating antibody-mediated neurological diseases. This core unit will be strongly interconnected with all subprojects, facilitate the exchange of concepts and provide infrastructural support. Medical staff will not only coordinate the entire path of CRU-associated patients through the hospital, but will also cover the individual antibody-mediated disease from early diagnostics to interdisciplinary work-up of the case (e.g. in the Neuroimmunology Board) to innovative individualized therapy. It will care for patients with all forms of antibody-mediated neurological diseases, such as autoimmune encephalitis, antibody-mediated dementia, neuromuscular disorders, neuromyelitis optica, developmental disorders related to autoantibodies, neuropsychiatric rheumatoid diseases, immune-mediated psychoses and antibody-related neuropathies.