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中文摘要
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摘要 行政核心的广泛目标是为有效运作提供基础设施, 通过促进协同和富有成效的互动,建立异源抗性跨学科研究单位(HR-IRU) 在调查员中。行政核心(核心A)对于帮助HR-IRU有效地实现其 长期目标是了解异源耐药的机制基础、动态和流行。的 核心的活动将由大卫韦斯和布鲁斯莱文博士领导,由戴安妮米勒女士和 珀尔·贝克曼核心A的目标由五个具体目标定义,沿着的还有人员配备和管理 布局这些目标将通过为各机构之间的业务后勤提供一个明确的结构来实现 和研究小组。HR-IRU由一支国际调查团队组成, 富有成效的合作历史,并将促进持续的沟通和协同互动 在研究项目和核心的研究人员中。核心A将执行和监督定期 视频会议、面对面会议和年度会议。为冲突建立了各种结构 决议、科学监督和通信后勤,以确保HR-IRU的有效运作。 HR-IRU的管理、协调和财务将在行政部门之间无缝运作, 埃默里大学和乌普萨拉大学的办公室和研究小组。计划已经到位,以保护 通过管理数据共享协议和互动,保护HR-IRU调查人员的知识产权 内部和外部的HR-IRU。建立了定期沟通和透明的框架 HR-IRU和NIH/NIAID项目工作人员之间的沟通,以及对NIH/NIAID请求的响应。 HR-IRU还旨在通过识别和寻找潜在的耐药性, HR-IRU调查人员与研究相关或相关现象的外部研究人员之间的合作。 这包括埃默里大学和乌普萨拉大学社区内的广泛交流, 通过在各种会议上介绍研究结果,以及邀请外部专家, 科学专家参加了该股的年度会议。行政部门执行的程序 这五个目标的核心和概述是建立在现有合作的基础上, 高度跨学科的单位和互动更广泛的社区,以成功地使 我们对异质抗性的理解有了根本性的进展。
英文摘要
ABSTRACT The broad objective of the Administrative Core is to provide infrastructure for the effective operation of the Heteroresistance Interdisciplinary Research Unit (HR-IRU) by facilitating synergistic and productive interactions amongst the investigators. The Administrative Core (Core A) is essential to help the HR-IRU efficiently meet its long-term goal of understanding the mechanistic bases, dynamics, and prevalence of heteroresistance. The activities of the Core will be led by Drs. David Weiss and Bruce Levin supported by Ms. Dianne Miller and Ms. Pearl Backman. The goals of Core A are defined by five specific aims, along with Staffing and Management Plans. The aims will be achieved by providing a defined structure for operational logistics between the institutions and research groups in the Unit. The HR-IRU is comprised of an international team of investigators with a strong history of productive collaboration, and will facilitate the continued communication and synergistic interactions among the investigators in the research projects and cores. Core A will implement and oversee regular videoconferences, face-to-face meetings, and annual meetings. Structures have been developed for conflict resolution, scientific oversight, and communication logistics to ensure effective operation of the HR-IRU. Management, coordination, and finances of the HR-IRU will operate seamlessly between the administrative offices and research groups at Emory University and the University of Uppsala. Plans are in place to protect the intellectual property rights of the HR-IRU investigators by managing data sharing agreements and interactions internally and externally to the HR-IRU. A framework is in place for regular communication and transparency between the HR-IRU and the NIH/NIAID program staff, and responsiveness to requests from the NIH/NIAID. The HR-IRU also aims to broaden the heteroresistance research community by identifying and seeking potential collaborations between HR-IRU investigators and external researchers studying related or relevant phenomena. This includes broad communications within Emory University and University of Uppsala communities, outreach to researchers through presentation of findings at meetings and conferences, and invitation of an external scientific expert to participating the Unit's annual meetings. The processes implemented by the Administrative Core and outlined by these five aims build upon existing collaborations to coordinate the smooth operation of the highly interdisciplinary Unit and interactions broader community, in order to be successful in making fundamental gains in our understanding of heteroresistance.
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Heteroresistance Interdisciplinary Research Unit (Project 2)
  • 批准号:
    10366038
  • 项目类别:
  • 资助金额:
    $35.85万
  • 财政年份:
    2021
  • 负责人:
    DAVID S WEISS
  • 依托单位:
CRISPR interference-enabled phenotyping of essential genes in C. difficile to aid in discovery of antibiotic targets
  • 批准号:
    10369416
  • 项目类别:
  • 资助金额:
    $20.86万
  • 财政年份:
    2021
  • 负责人:
    DAVID S WEISS
  • 依托单位:
CRISPR interference-enabled phenotyping of essential genes in C. difficile to aid in discovery of antibiotic targets
  • 批准号:
    10518406
  • 项目类别:
  • 资助金额:
    $17.38万
  • 财政年份:
    2021
  • 负责人:
    DAVID S WEISS
  • 依托单位:
Heteroresistance Interdisciplinary Research Unit (Project 2)
  • 批准号:
    10583505
  • 项目类别:
  • 资助金额:
    $55.09万
  • 财政年份:
    2021
  • 负责人:
    DAVID S WEISS
  • 依托单位:
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